Tag Archives: autoimmune diseases

A new hypothesis of autoimmune diseases: stress and the nucleolus

Autoimmune diseases (AIDs) have complicated pathologies influenced by genetic, epigenetic and environmental factors. Mechanisms of AIDs remain mysteries but numerous hypotheses have been proposed. Several hypotheses are discussed to present their unique explanations and to demonstrate that

The roles of α2AP in the pathogenesis of systemic sclerosis

Systemic sclerosis (SSc) is autoimmune rheumatic disease of unknown etiology that is characterized by the fibrosis of skin and visceral organs, and peripheral circulatory disturbance. In our study, we found that alpha2-antiplasmin (α2AP), which is known to

Arrestin-enolase protein complex as a new auto antigen in heart disease

Over the past two decades, evidence of a pathogenic relevance of autoimmunity in human heart disease has increased significantly. A central role for autoimmunity in a significant proportion of dilated cardiomyopathy (DCM) patients is supported by the