Tag Archives: breast
Does tangential radiation for breast cancer cover internal mammary nodes?
Breast cancer is one of the most common cancers in women in the United States. Radiation is a very commonly used treatment modality for breast cancer: it is offered to nearly all patients after lumpectomy (removal of
Altered methylation in Breast Cancer in very young women
Breast cancer has the highest incidence rate of all cancers in women worldwide. Although early breast cancer generally has an excellent prognosis, breast cancer in young women (under the age of 35) is associated with a high
An integrated genomics approach for identifying breast cancer patients with highly aggressive tumors
Breast cancer is the most common cancer in women with over 2 million new cases worldwide in 2018. Three kinds of receptors are usually found on the surface of breast cancer cells: a receptor for female hormone
Compressed ultrasound imaging: finding tumors with a few transducers
Currently, ultrasound imaging is predominantly done by a probe that possesses many transducers, which are small devices that transmit, and then receive, acoustic waves. Decreasing the number of transducers, while maintaining image quality, is surely a desirable
Keeping a clean house to suppress HER2+ breast tumor growth
Autophagy (self-eating) is a process used by normal cells to keep a “clean house”. It degrades abnormal or damaged proteins and organelles, helps to fight infections and also provides energy during periods of fasting or exercise. Besides
A new biomarker for Triple negative breast cancer MCP-1 drives cancer invasiveness and metastasis
Breast Cancer is the second leading cause of mortality in women in the United States. Breast cancer arise in the ducts of the mammary glands that produces milk in a lactating breast. Breast cancers usually express various
Grandmothers’ breastfeeding stories to mothers: a knowledge translation gift
Breastfeeding is an ideal way to feed babies that promotes and protects health throughout life. In the Northwest Territories, Canada, in follow-up to a study from one region of the territory, we conducted a territory-wide study to
Adopting mammary development gameplay in breast cancer initiation and progression
The process by which the breast changes during puberty and lactation is incredibly unique. Those changes are essential for the functional mammary gland. These changes are triggered and orchestrated by hormones. Such hormonal changes start during pregnancy
Potential biomarkers of CDK4/6 inhibitors in HR-positive advanced breast cancer
Thanks to the development of endocrine therapy, the mortality rate of estrogen receptor (ER)-positive breast cancer patients has been decreased drastically. In spite of the improvement, however, relapse and progression that are driven by different mechanisms are
Transmitted sound wave mammography
This study was designed to look at a new type of totally harmless breast imaging called whole-breast transmission ultrasound to see if it could do something mammography cannot do – that is to diagnose the presence of
Next generation sequencing, a new gold standard for clinical gene panel testing
The adaption of the Next Generation Sequencing ( NGS ) technology to clinical laboratories has revolutionized the molecular diagnostics by reducing the costs and increasing the throughput. Clinical use of NGS enables simultaneous testing of multiple genes
The synergistic role of prolactin and estrogen in breast cancer requires PAK1
In 2016, the American Cancer Society estimates about 40,000 deaths will result from breast cancer. This makes breast cancer the second leading cause of cancer-related among women. Despite the frightening statistics, the death rates from breast cancer
A promising novel drug for breast cancer
The reason cancer is so difficult to treat is that cancer cells are our own cells running wild, which means that they generally do not make any protein or other molecule that normal cells don’t make. This
Screening breast MRI in patients with personal history of breast cancer
This study looked at patients who had a personal history of breast cancer diagnosed at a premenopausal age to see if having screening breast MRI provided a benefit to the patient. Patients with a personal history of
Type of breast cancer provides clues to genetic susceptibility
Breast cancer is a common disease affecting 1 in 11 women in the UK but like many common cancers incidence increases with increasing age. Only 1 in 1,700 women younger than 30 and 1 in 228 women
Omega-3 fatty acids, obesity and breast density
Omega-3 fatty acids, abundantly present in fish oil products, are in large use among the public because of the widespread perception that they are able to ameliorate and even prevent many chronic diseases, including cancer. Our research
Importance of updating prognostic predictions: an example from breast cancer
Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk
A novel protein called nischarin
Nischarin is a large protein that is present in the nucleus and cytoplasm of cells. So far, diseases associated with the NISCH gene include hypertension, dry mouth, morphine dependence, depression, anxiety, thick heart walls, congestive heart failure,
Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer
Stage IV breast cancer is the state in which the cancer has spread to distant sites , for example , the brain, liver, lung, bones. Treatment for stages I to III of breast cancer include surgery, chemotherapy
