Tag Archives: cAMP

Do you want a specific signal? Go local! Imaging our way to targeted therapy

Cyclic adenosine monophosphate (cAMP) is a ubiquitous intracellular second messenger, a small molecule that conveys the information carried by hormones, neurotransmitters and other extracellular stimuli to the intracellular environment. cAMP is generated at the plasma membrane when

Old drugs learn new tricks: drug repurposing saves the world!

New way of drug discovery, “drug repurposing” has come into the spotlight. Drug repurposing—also known as drug reprofiling or drug repositioning—is essentially using “old” drugs to treat “new” diseases. With increases in knowledge about the molecular mechanisms

Big tasks for small flies: signaling cascades may help insects to detect faint odor traces

Have you ever wondered how a tiny vinegar fly manages to find its way to a ripened fruit in your kitchen? As many other insects flies possess a very keen sense of smell, which allows them to

PDE2 is a potential new target for the treatment of cardiac hypertrophy

Heart failure is one of the leading causes of death in the Western World today. It typically involves a deficiency of the heart to provide sufficient blood flow and/or blood pressure to meet the requirements of the