Tag Archives: cytoskeleton
EML1: an entry point to study cellular mechanisms at the origin of brain malformations
Cerebral cortical development is a tightly regulated process, depending on dividing progenitor cells that ultimately produce neurons that then migrate to find their appropriate positions in the developing cortex. Certain genetic conditions as well as environmental factors
Cell Movement: It’s all a balancing act!
Although it may appear solid, the human body is full of moving cells. For example, the mass migration of cells helps shape the human body in the womb. Skin cells crawl towards each other during wound healing
Live-cell imaging revealed the dynamics and the roles of cytoskeleton in polarizing plant zygote
Asymmetric cell division is one of the fundamental steps to form the plant body axis. In most flowering plants, the apical-basal axis is established by the asymmetric division of the zygote. In a model plant Arabidopsis thaliana,
How the extracellular matrix affects the cells within us
All animals, including humans, are affected by the environment in which they live—the cells within our bodies are no different. Cells live in a dynamic fibrous and fluid network that contains many biopolymers that provide structural support
How do bacteria divide and multiply?
Bacteria interact with our bodies every day, resulting in both positive and negative outcomes. We rely on the billions of beneficial bacteria in our microbiome to support our digestion and immunity. At the same time, pathogenic bacteria
Guanine-nucleotide exchange factor that promotes loss of polygonal cell shape
Actin cytoskeleton dynamics determines cell shape and movement. Fibroblasts or epithelial cells, for instance, adhere and spread onto planar surfaces adopting an elongated polygonal shape. Underneath the cytoplasmic membrane, local activation of small GTPase enzymes of the
Oligodendrocyte Tau’s failed quest for microtubules results in myelin decrease and falling
Oligodendrocytes make a good-sized myelin that surrounds axons and allows humans to walk and see. In contrast, when axons do not get enough myelin, axonal function is incapacitated, with resulting deficits in cognition, behavior, and in the
