Tag Archives: diabetes

Why photobiomodulation therapy is helpful for diabetic wound healing? Fibroblast answers!

AoS. diabetic wound healing

It is an obvious well-known issue that diabetic wounds are poorly healing, but the molecular and cellular alterations leading to this impairment is not clear. Many studies concluded the dysfunction of dermal fibroblasts as the main responsible

The roles of mesenchymal stem cells secretome in diabetic wound healing

AoS. The Roles of Mesenchymal Stem Cells Secretome in Diabetic Wound Healing.

There has been a fourfold rise in the number of diabetics from 108 million in 1980 to 422 million in 2014 and by 2040 the number will reach to 642 million. Diabetes mellitus drastically influences normal functioning

3D-bioengineered human amniotic membrane scaffold for improvement of wound healing in diabetic rats

AoS. 3D-bioengineered human amniotic membrane scaffold.

In the tissue engineering context, attention to the biological scaffolds due to the safety, efficacy, and bio-mimicity was discussed. Among the natural scaffolds, human amniotic membrane (HAM) has shown to be promising and has been used for

Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

AoS. Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

Type 2 diabetics are at increased risk of cancer in part because of increased insulin in the blood from insulin resistance. Insulin and its related growth factor IGF-1 can stimulate cell growth through the Ras-Raf-MEK-ERK or the

Kelp extracts and their pharmaceutical properties

Kelp extracts and their pharmaceutical properties. AoS

Kelps are a specific type of large brown seaweeds that generally grow on rocky, shallow, nutrient-rich ocean water. The most common examples of kelps found in the South African coastlines include Ecklonia maxima (sea bamboo) (Fig. 1), Ecklonia

Early detection of “insulin balls” using ultrasonography

Early detection of “insulin balls” using ultrasonography. AoS

Diabetes patients often suffer from subcutaneous induration at insulin injection sites during insulin therapy. Among the different types of subcutaneous complications of insulin injection, lipohypertrophy and insulin-derived amyloidosis (IDA) are defined as tumor-like enlargements of adipose tissue

3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats

In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was

Plasma CTSD activity: a non-invasive biomarker for hepatic insulin sensitivity

type 2 diabetes. AoS

Due to the obesity epidemic, the incidence and prevalence of type 2 diabetes mellitus continues to rise globally. Type 2 diabetes is characterised by a relative insulin deficiency and an impaired insulin sensitivity in certain specific target organs. Insulin sensitivity can

Can “low calorie”-oil enhance the secretion of incretin hormones with beneficial effects on diabetic patients?

Time courses for plasma GLP-1 following ingestion of olive oil and carrot (squares), C4-dietary oil and carrot (circles) and carrot alone (crosses).

When the human body digests dietary fat (triacylglycerol), hormones from the intestine called incretins are released from the small intestine. These hormones stimulate insulin release and inhibit food intake. The mechanism for the fat-induced incretin release involves

Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed

Risk of non-alcoholic fatty liver disease in patients with type-1 diabetes

In this modern world non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease. It is defined as the presence of fatty liver disease in the absence of excess alcohol or

Not frozen in time: the past matters to the relationship between body weight and insulin

Insulin is a hormone which regulates how your food fuels your body. The food you eat is digested and converted into glucose, which then travels through your blood to reach all of the organs and tissues in

The role of oxidative stress in Type 2 diabetes

Type 2 diabetes is a major health concern that affects people no matter their gender, race, or socio-economic background is. In type 2 diabetes, a person’s body stops responding efficiently to insulin after a meal. This desensitization

Assessing the evidence on weight loss strategies

Weight loss and weight management is of upmost importance in our current climate of increasing rates of overweight and obesity and of associated diseases like type 2 diabetes. Here the evidence on weight loss strategies, in people

Bimetallic nanoparticles-based biosensor for managing diabetes

The glycated hemoglobin test gives the information about average level of blood sugar over the past 2 to 3 months. It’s also called HbA1c, glycated hemoglobin test, and glycohemoglobin. Persons who have diabetes require this test regularly

B-vitamins over-consumption may be the cause of the increased prevalence of obesity and diabetes

Obesity and type 2 diabetes have been a major health issue in the United States. It is during the past few decades that obesity and type 2 diabetes have rapidly reached epidemic levels not only in adults

Does statins increase risk of diabetes?

Statins are drugs that inhibit the enzyme 3-Hydroxy-3-methylglutaryl-coenzymeA (HMG-CoA) which is critical in the production of cholesterol molecules. Thus is commonly used in the treatment of abnormally elevated cholesterol which is known to contribute to cardiovascular disease

Modern medicine is poisoned by professional arrogance

Modern medicine is poisoned by professional arrogance. The antidote is professional humility. The arrogance is exacting a high price. Several examples prove the point. For forty years physicians regularly irradiated the thymus glands of children because of

The most effective system to weight lost

People who suffer from morbid obesity are at high risk for many diseases, atherogenic dyslipidemia, elevated blood pressure, type 2 diabetes, thromboembolism, hepatic steatosis, proinflammatory state, etc. Metabolic syndrome is characterized by the clustering of some, or

Electrically controlled insulin release

Stimuli responsive materials are promising for designing the next generation of drug delivery systems. Such materials would enable drugs to be released on-demand or in response to patient needs, specifically at the target site, minimizing side effects.