Tag Archives: diabetes

Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?

AoS. Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?

Glucocorticoids are medications widely used to treat inflammation and allergies, and in contexts of immunosuppression such as after transplants. They are well-established and safe. The problem is that, when used for a long time, or in high

Naturally occurring peptide may tackle the “root cause” of obesity-related diseases

Obesity typically occurs when a person eats more calories than they need for their daily activity. It results in a build-up of fatty tissue around all organs. In lean people, fat tissues work closely with hormones to

Am I at risk of developing diabetes if exposed to insecticide?

AoS. Am I at risk of developing diabetes if exposed to insecticide?

The answer is: it depends. Of course, there is no trivial answer to an open question like that when referring to scientific investigation. But we can make you think better before exposure to certain pesticides like malathion.

A mixture of plant extracts attenuates postprandial glycemia

AoS. A mixture of plant extracts attenuates postprandial glycemia

The epidemiological studies demonstrate beneficial effects of a regular consumption of fruits, vegetables or grains on human health, which is usually a result of their lower caloric value and dietary fiber and specific bioactive compounds present in

Should You Get a Glucometer?

AoS. Should You Get a Glucometer

Monitoring your body glucose level gives you essential information about how diet, exercise, medications, and other aspects can affect your health. As diabetes can last a lifetime, using a glucometer is beneficial. The data in the glucometer

Nutritional strategies in managing postmeal glucose for Type 2 Diabetes mellitus

The postmeal hyperglycemia is a common feature of Type 2 Diabetes (T2D) with the majority of the patients have not achieved the postmeal target of less than 7.8 mmol/L at 2h. While the role of Medical Nutrition

Chronic unpredictable environmental stress is harmful to humans

Stress refers to the mental and emotional change of state from normal homeostasis. In another words we can say that stress happens when we are worried for something and feeling uncomfortable. Chronic unpredictable environmental stress (CUES) refers

Novel genetics approach identifies GNAS gene as an important prerequisite for β-cell secretory capacity

AoS. Novel genetics approach identifies GNAS gene.

Type 2 diabetes mellitus (T2D) is a major health burden in developing and industrialized countries (www.idf.org). Common genetic variations, susceptibility genes, epigenetic regulation, and miRNAs have been suggested to be profoundly involved in the pathogenicity of T2D. 

Targeted GRP78 pathway for improved vision in diabetic retinopathy

AoS. Targeted GRP78 pathway for improved vision in diabetic retinopathy.

Diabetic retinopathy, is a complication of diabetes which causes vision loss and eventual blindness in adults. People with diabetes have more sugar in their blood than normal, which causes their bodies not to function correctly. Often proteins

Why photobiomodulation therapy is helpful for diabetic wound healing? Fibroblast answers!

AoS. diabetic wound healing

It is an obvious well-known issue that diabetic wounds are poorly healing, but the molecular and cellular alterations leading to this impairment is not clear. Many studies concluded the dysfunction of dermal fibroblasts as the main responsible

The roles of mesenchymal stem cells secretome in diabetic wound healing

AoS. The Roles of Mesenchymal Stem Cells Secretome in Diabetic Wound Healing.

There has been a fourfold rise in the number of diabetics from 108 million in 1980 to 422 million in 2014 and by 2040 the number will reach to 642 million. Diabetes mellitus drastically influences normal functioning

3D-bioengineered human amniotic membrane scaffold for improvement of wound healing in diabetic rats

AoS. 3D-bioengineered human amniotic membrane scaffold.

In the tissue engineering context, attention to the biological scaffolds due to the safety, efficacy, and bio-mimicity was discussed. Among the natural scaffolds, human amniotic membrane (HAM) has shown to be promising and has been used for

Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

AoS. Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

Type 2 diabetics are at increased risk of cancer in part because of increased insulin in the blood from insulin resistance. Insulin and its related growth factor IGF-1 can stimulate cell growth through the Ras-Raf-MEK-ERK or the

Kelp extracts and their pharmaceutical properties

Kelp extracts and their pharmaceutical properties. AoS

Kelps are a specific type of large brown seaweeds that generally grow on rocky, shallow, nutrient-rich ocean water. The most common examples of kelps found in the South African coastlines include Ecklonia maxima (sea bamboo) (Fig. 1), Ecklonia

Early detection of “insulin balls” using ultrasonography

Early detection of “insulin balls” using ultrasonography. AoS

Diabetes patients often suffer from subcutaneous induration at insulin injection sites during insulin therapy. Among the different types of subcutaneous complications of insulin injection, lipohypertrophy and insulin-derived amyloidosis (IDA) are defined as tumor-like enlargements of adipose tissue

3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats

In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was

Plasma CTSD activity: a non-invasive biomarker for hepatic insulin sensitivity

type 2 diabetes. AoS

Due to the obesity epidemic, the incidence and prevalence of type 2 diabetes mellitus continues to rise globally. Type 2 diabetes is characterised by a relative insulin deficiency and an impaired insulin sensitivity in certain specific target organs. Insulin sensitivity can

Can “low calorie”-oil enhance the secretion of incretin hormones with beneficial effects on diabetic patients?

Time courses for plasma GLP-1 following ingestion of olive oil and carrot (squares), C4-dietary oil and carrot (circles) and carrot alone (crosses).

When the human body digests dietary fat (triacylglycerol), hormones from the intestine called incretins are released from the small intestine. These hormones stimulate insulin release and inhibit food intake. The mechanism for the fat-induced incretin release involves

Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed

Risk of non-alcoholic fatty liver disease in patients with type-1 diabetes

In this modern world non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of chronic liver disease. It is defined as the presence of fatty liver disease in the absence of excess alcohol or