Tag Archives: DNA synthesis

Identification of a novel factor implicated in the resistance of cancer to the therapy

Therapeutic treatment of cancer involves radiotherapy and/or chemotherapy so to generate a large amount of lesions in the DNA. Because cancer cells have reduced capacity to repair DNA lesions and are unable to slow down proliferation, this

Mitochondrial POLG2 disease mutations impair cellular energy supply

Mitochondrial diseases are devastating disorders for which there is no cure and no proven treatment. About 1 in 2000 individuals are at risk of developing a mitochondrial disease sometime during the course of their life. Half of

Geology’s latest gift to molecular biology?

Only a few hardy bacteria and archaea make their home in geothermal springs, but the enzymes of these thermophiles have for decades benefitted biological research.  While the value of the bacterial DNA polymerase “Taq” in amplifying DNA