Tag Archives: fibroblast

Why photobiomodulation therapy is helpful for diabetic wound healing? Fibroblast answers!

AoS. diabetic wound healing

It is an obvious well-known issue that diabetic wounds are poorly healing, but the molecular and cellular alterations leading to this impairment is not clear. Many studies concluded the dysfunction of dermal fibroblasts as the main responsible

The roles of mesenchymal stem cells secretome in diabetic wound healing

AoS. The Roles of Mesenchymal Stem Cells Secretome in Diabetic Wound Healing.

There has been a fourfold rise in the number of diabetics from 108 million in 1980 to 422 million in 2014 and by 2040 the number will reach to 642 million. Diabetes mellitus drastically influences normal functioning

3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats

In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was

Fibroblasts in rheumatoid arthritis: From friend to foe

Fibroblast effects on leukocytes

Our joints are composed of tissue-resident cells, called fibroblasts, which are responsible for maintaining the structure of the joint and repairing damaged tissue. Additionally, we and others have shown that fibroblasts can also influence the types and

Perlecan HS produces TGF-β1 deficiency in mutant skin

The skin is the largest organ in the human body and one of it’s most dynamic. Skin has a large surface area and protects the body from the external environment and is challenged by many poisonous substances

PDGF-D – a potential novel treatment for kidney diseases with scaring

Estimates suggest that a huge number of people, more than 10% of the world-population, are suffering from chronic kidney disease. Chronic kidney disease eventually leads to complete loss of kidney function, which is fatal if not treated

Metabolic regulation by the intestinal hormone FGF19: From basic science to clinical application

Physiological adaptations of our body to changes in nutritional status induced by fasting or food intake occur various times per day and are crucial to maintain a healthy metabolic state. To meet this requirement, our body is

Characterisation of the human epicardium in the developing heart

The vertebrate heart is composed of three cell layers: an inner layer lining the heart chambers (atria and ventricles), the endocardium; an intermediate muscle layer, the myocardium; and an outer layer that envelops the myocardium, the epicardium.