Tag Archives: G-quadruplex

The RAS mRNA G-quadruplex: making undruggable cancer targets druggable

The RAS mRNA G-quadruplex. AoS

In many cancers, RAS proteins are constitutively activated by their oncogenic mutations or activation of their upstream molecules. RAS proteins play a central role in cancer cell malignancy, and drugs that target RAS are therefore believed to

Folding of DNA strand controlled by designed stimuli

Folding of biomolecule strands (such as proteins and nucleic acids) play important fundamental role in emerging their functions such as binding to the partner molecules (only folded structures can have function to bind the partner molecules) to