Tag Archives: glucocorticoids
Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?
Glucocorticoids are medications widely used to treat inflammation and allergies, and in contexts of immunosuppression such as after transplants. They are well-established and safe. The problem is that, when used for a long time, or in high
Glucocorticoids as a double-edge sword in the inflamed intestine
Chronic intestinal inflammation, in the form of the conditions ulcerative colitis and Crohn’s disease, is relatively common. Glucocorticoids (GCs) are the therapy of choice for the treatment acute flares of these diseases, but they have significant limitations,
Stress, sex, and sunlight – a different perspective on vitamin D
Low levels of vitamin D in the blood have been associated with a high risk of developing several diseases, including autoimmune diseases, cardiovascular diseases, neurodegenerative diseases, and cancer. Our study group has been working on the role
Osteoporosis in childhood
It is well known that bones tend to become brittle with ageing. Less well-known is that children also suffer from fractures resulting from little or no force to provoke the injury. The cause in some children is
Increased stress hormone exposure can be beneficial
Under challenging circumstances, such as predator exposure or lack of food, animals naturally secrete stress hormones. Production, secretion and release into the bloodstream of these hormones is tightly regulated by the Hypothalamic-Pituitary-Adrenal axis (the stress axis), a
