Tag Archives: hippocampus
Poverty may affect the developing brain through chronic stress
Socioeconomic disadvantage, which is prevalent in the United States and worldwide, is consistently associated with lower academic achievement and higher risk for emotional and behavioral problems. Exposure to socioeconomic disadvantage during childhood can leave long-lasting imprints on
Cannabinoid receptors and incidental associations: a way to creativity?
Animals and humans adapt to changes in the environment through previous experiences. In our daily life, while we are engaged in a particular activity or social event, we are continuously surrounded by random associations between low salience
Phage therapy: a one-hundred-year-old alternative to modern, chemical antibiotics
Phage therapy is the use of bacterial viruses, known as bacteriophages, or phages, to control or eliminate problematic bacteria (Fig. 1). Targeted bacteria can range from biofouling agents to agricultural pests to human pathogens, etc. As has
The new subregion in parahippocampal region founded integrated the two memory-related brain networks
The parahippocampal region (PHR) is an interface region between the hippocampus and the neocortex located in the medial temporal lobe (MTL). The PHR has been implicated in many functions, including long-term memory, working memory, and perception. Given
Alzheimer’s disease or type 2 diabetes?
Alzheimer’s disease (AD) is one of the most common causes of senile dementia and it is estimated that by 2050, the number of cases will rise to 110 million. The vast majority of patients suffer from the
Age-dependent impairments in spatial learning in mice with reduced BDNF levels
The protein BDNF (brain-derived neurotrophic factor) belongs to the family of nerve growth factors (neurotrophins). Therefore, one of its major functions is related to the maturation and differentiation of developing nerve cells in the brain. But BDNF
Isovaline, a compound first identified in the Murchison meteorite, shows potential for treating Epilepsy
Epilepsy is a brain disease that affects 65 million people worldwide and is characterized by seizures that arise from hyper-active and hyper-connected brain cells. Typically, the first approach for managing seizures is treating individuals with pharmaceuticals. However,
A link between reduced blood oxygenation and failure in learning and memory in a mouse model of Down syndrome
Down Syndrome (DS) is the most frequent genetic cause of cognitive disability in humans, affecting more than 6 million people worldwide. Triplication of more than 300 genes on chromosome 21 results in gene dosage imbalance that affects
Septo-hippocampal signal processing
If we are ultimately to uncover how the brain encodes the information about the surrounding environment it is necessary to understand how the spatial signals are being processed and regulated. The hippocampal region plays a crucial role
