Tag Archives: hippocampus

Phage therapy: a one-hundred-year-old alternative to modern, chemical antibiotics

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Phage therapy is the use of bacterial viruses, known as bacteriophages, or phages, to control or eliminate problematic bacteria (Fig. 1). Targeted bacteria can range from biofouling agents to agricultural pests to human pathogens, etc. As has

Do you get lost?

Many people get lost in unfamiliar surroundings, and many others have problems to find their car in large parking lots. However, certain individuals get lost in places that they are supposed to know intimately, such as their

The new subregion in parahippocampal region founded integrated the two memory-related brain networks

The parahippocampal region (PHR) is an interface region between the hippocampus and the neocortex located in the medial temporal lobe (MTL). The PHR has been implicated in many functions, including long-term memory, working memory, and perception. Given

Alzheimer’s disease or type 2 diabetes?

Alzheimer’s disease (AD) is one of the most common causes of senile dementia and it is estimated that by 2050, the number of cases will rise to 110 million. The vast majority of patients suffer from the

Age-dependent impairments in spatial learning in mice with reduced BDNF levels

The protein BDNF (brain-derived neurotrophic factor) belongs to the family of nerve growth factors (neurotrophins). Therefore, one of its major functions is related to the maturation and differentiation of developing nerve cells in the brain. But BDNF

Isovaline, a compound first identified in the Murchison meteorite, shows potential for treating Epilepsy

Epilepsy is a brain disease that affects 65 million people worldwide and is characterized by seizures that arise from hyper-active and hyper-connected brain cells. Typically, the first approach for managing seizures is treating individuals with pharmaceuticals. However,

A link between reduced blood oxygenation and failure in learning and memory in a mouse model of Down syndrome

Down Syndrome (DS) is the most frequent genetic cause of cognitive disability in humans, affecting more than 6 million people worldwide. Triplication of more than 300 genes on chromosome 21 results in gene dosage imbalance that affects

Septo-hippocampal signal processing

If we are ultimately to uncover how the brain encodes the information about the surrounding environment it is necessary to understand how the spatial signals are being processed and regulated. The hippocampal region plays a crucial role