Tag Archives: hypertension
Investigating SOCS3 as a new target for drugs to treat pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a fatal disease caused by the walls of the small blood vessels that supply the lungs walls becoming thicker (Fig. 1) and unable to adapt to changes in blood flow, resulting in
Na/K pump mutations lead to hypertension by impairing Na+ and K+ transport
Aldosterone is a hormone that regulates blood pressure by increasing the amount of salt and water that your body retains as blood is filtered through the kidney. Aldosterone is produced by specific cells in the adrenal gland
Angiotensin II actions on distal regulatory elements promote vascular dysfunction and hypertension
Cardiovascular diseases such as hypertension (high blood pressure) and atherosclerosis (blocked blood vessels) lead to heart attacks and strokes, and are highly prevalent worldwide. Furthermore, these complications are significantly accelerated in patients with diabetes. Angiotensin II (AngII)
Mechanisms of diuretic plants: an overview
Ongoing research suggests several molecular mechanisms that were correlated with acute or prolonged diuretic activity of different natural products. So, it is not surprising that research on this subject is at the forefront of research on the
Malaria and hypertension-a new hypothesis in clinical medicine
Research from University College Cork, Ireland and New York University School of Medicine, USA has shown a credible link to the high rate of hypertension, stroke, and myocardial infarction amongst Africans and Afro-Americans, and a genetic defence
Blood pressure charts for pediatrics
Blood pressure screening is essential throughout life. Adult blood pressure assessments have static thresholds of 140/90 for hypertension and 90/60 for hypotension but screening blood pressure in children is more complicated. As children grow, normal blood pressure
How sugar and fat affect our brain leading to a high blood pressure?
Obesity is a serious, chronic and pandemic disease that can have a negative effect on many systems in our body. People who are overweight or obese have a much greater risk of developing serious diseases including hypertension.
Vitamin D3 supplementation and blood pressure: a meta-analysis
Hypertension is a chronic condition that can lead to renal disease, cardiovascular disease, stroke and mortality. Vitamin D plays an important role in regulation of calcium and bone homeostasis and associated with mortality, type 2 diabetes, metabolic
A surgical treatment for high blood pressure
According to the Center for Disease Control and Prevention, 70 million Americans are diagnosed with high blood pressure, also referred to as hypertension in the medical field. The majority of these individuals are not experiencing any symptoms
Risk factors of hypertension amongst adults in rural areas of South Africa
Cardiovascular disease (CVD) is now the leading cause of death worldwide, and its major impact is not only observed in developed countries but also in developing countries. In 2008, CVD caused 30% of all global deaths, of
Melatonin reduces blood pressure and tunes up disrupted circadian rhythms in the seniors
The older we get the more likely our circadian rhythms are disrupted. For example, blood pressure not only tends to increase but as well become more irregular. Luckily, as we show here, melatonin helps to ameliorate both
G protein signaling: a major culprit of essential hypertension
Blood pressure (BP) is the driving force that distributes the blood to the organs of the body according to their instantanous needs. It may be increased by pressor agents acting on the heart, vessels, and blood volume,
Can hypertension and related cardiovascular diseases be caused by Dark-Matter-like RNAs?
Hypertension is a common but one of the most important health problems, because it is a major risk factor for many cardiovascular diseases. Hypertension is a multi-factorial disease involving complex interplay of genetic and environmental factors. To treat
Kidney angiotensinogen as a cardinal risk factor in hypertension
High blood pressure is prevalent in over 30% of the adult population and accounts for approximately one fourth of patients with heart failure, especially the elderly. The renin-angiotensin system (RAS) is of critical importance in the regulation
High blood pressure is controlled more effectively by two drugs in one pill
Hypertension, or high blood pressure (BP), is a major global public health problem, both because of how common it is and its correlation with cardiovascular disease. It has been identified as one of the major risk factors
