Tag Archives: IL-10

Skewed signaling through RAGE strength the tumor growth-promoting activities of M2 macrophages

Skewed signaling through RAGE strength. AoS

Tumors are complex tissues composed by both non-cellular components, mainly matrix proteins, and different stromal cell types, which are under an active cross talk with tumor cells. Tumor-associated macrophages (TAMs) are the major leukocyte population among the

Immunological changes associated with hepatocellular carcinoma development

Immunological changes associated with Hepatocellular Carcinoma development

The body’s immune defense mechanisms play an important role in the inhibition or progression of liver diseases. We assessed the expression levels of different immune cells and cytokines in patients with chronic hepatitis C (CHC), liver cirrhosis

Can we treat cancer by targeting Treg subset without causing autoimmune disease?

The regulatory T cells (Tregs), are a type of CD4+ T cells that suppress the potentially adverse effect of the immune system and prevent autoimmune disease. Although they play a central role in maintaining self-tolerance, Tregs also