Tag Archives: immunohistochemistry

The immunomodulatory enzyme IDO: Expression in the uterus of mares?

Detection of IDO protein in the equine endometrium by immunohistochemistry

IDO modulates immune responses. The enzyme indoleamine 2,3-dioxygenase 1 (IDO) degrades tryptophan. This amino acid is required for immune defences against pathogens, but also stimulates pathogen growth. Its degradation inhibits effector lymphocytes and retards pathogen proliferation. Thus,

Blue nevus of the uterine cervix – a melanocytic lesion corresponding to cutaneous blue nevi

Blue nevi are benign melanocytic disorders, which commonly present cutaneous lesions and rarely arise in female genital tracts. To date, although several cases of endocervical blue nevi have been reported, their biological nature is not sufficiently clarified.

Diagnosis of small cell lung carcinoma metastases

Cancer is defined by unscheduled cellular growth and metastatic spread into other organs of the body. Tumor cells gain their capacities form genetic alterations, also known as mutations, leading to altered protein functions and signaling pathways. Tumors