Tag Archives: lung

How does histamine make it hard to breathe?

Histamine is a chemical substance that can be released in the lungs to cause narrowing of the bronchial tubes and difficulty breathing. Airway smooth muscle cells in the bronchioles (small airways) of the lung can contract or

A potential radiotracer for imaging the lungs

Routine patient lung scans in the nuclear medicine department have for decades, employed a radioactive technetium-99m-aggregated-albumin particle injection dose, in conjunction with a ventilation dose of Tc-99m-aerosol in tandem. The lung scans are usually requested for patients

The use of bone marrow-derived mononuclear cells ameliorates airway inflammation in horses with recurrent airway obstruction

Horses stabled indoors live in a pro-allergenic environment and are exposed to molds, mites, and bacterial endotoxins from hay and bedding. This exposure exacerbates recurrent airway obstruction (RAO), an asthma-like disease. Affected horses suffer from recurrence of

Treatment of sarcoidosis

Sarcoidosis is an uncommon, poorly understood disorder that most often affects the chest. Its cause is unknown. While the outcome is, in general, favorable, a small number develop scarring of the lungs (fibrosis), which, if extensive, will

The reality of latent tuberculosis bacillus?

Tuberculosis is caused by the infectious agent known Mycobacterium tuberculosis (Mtb) (Fig. 1). This rod-shaped bacterium, also called Koch’s bacillus, was discovered by Dr. Robert Koch in 1882. When a person breathes in Mtb-contaminated air, the inhaled TB bacteria

A mild form of dermatomyositis as a prodromal sign of lung cancer: looking behind the skin

Dermatomyositis is a rare inflammatory disease characterized by specific skin findings and inflammatory lesions in the muscle biopsy. The most common clinical signs of dermatomyositis include an erythema over the face, neck and upper trunk known as

Improving the care of lung cancer patients who need major surgery

We report the impact of several factors on procedure times for major lung surgery for cancer, focusing on staff turnover within the surgical team. We propose a new definition of surgical team turnover which allows us to

Cultured macrophages help predict lung toxicity of inhaled nanoparticles

Many small particles of industrial or occupational origin are believed to infer an inflammatory or otherwise toxic potential to human health upon inhalation. Knowledge on this issue is especially important for the very small nanoparticles, which measure

Using computers to understand the deposition of pollutant and therapeutic aerosols in the human lungs

In an urban setting, suspended pollutant particles enter our lungs along with air we inhale.   A good portion of them gets deposited on our airways, often inducing toxic effects. A young child or an elderly patient facing

Fish gills help understand human lung disease

Persistent inflammation of the lung leads to fibrosis, a serious and poorly understood disease that causes scarring of the lungs. A poor prognosis of only approximately 3 years survival after diagnosis demonstrates the lack of understanding of

Fluorescent carbon dots integrated hydrogels for lung cancer therapy

Cancer is considered as one of the leading cause of death worldwide. Due to the ever changing lifestyle of the modern society, the incidence of cancer is on the rise. Lung cancer is the most frequently diagnosed

Three dimensional quality assurance protocol for thoracic and genitourinary radiation therapy

After cancer diagnosis one treatment option is the use of external radiation. As the radiation traverses the patient it deposits most of its energy in the tumor, which causes irreparable damage to the cancer cells. One type

The use of multisite ultrasound in cardiac arrest – the SESAME-protocol

Cardiac arrest is the most critical emergency. The sudden interruption of oxygen supply damages the brain after some minutes. Finding a cause for efficiently fixing the problem is the main target of the frontline physician. Ultrasound is

Side effects of radiation therapy: Why me?

Most lung cancers are treated with radiation therapy, often in high doses.  Although these treatments are absolutely required to prolong life (by killing the tumor or slowing its growth), radiation treatment can have negative side effects that

The many faces of macrophages in lung cancer

Lung cancer is the leading cause of cancer death worldwide, accounting for more deaths than breast, prostate, and colon cancer combined. Within the past decade, the role of the immune system in the development and progression of

Diminished disease-free survival following lung cancer surgery

Treatment of lung cancer requires removal of a portion of a vital organ, which may reduce life expectancy. This would be acceptable when surgery prevents death from cancer. It is harmful in cases identified by screening in