Tag Archives: lymphocytes

The doors of the cell’s nucleus play a critical role in the survival and function of immune cells

Model showing the effect of Nup210 ablation in mouse CD4 T lymphocytes

Our immune system has a fascinating ability to distinguish between what does or does not belong to our body. This ability allows it to fight off infectious agents without harming our own cells. T cells are key

Inhibitors of intracellular enzymes for treatment of multiple sclerosis

The protein kinase inhibitor imatinib

Lymphocytes are white blood cells that are central in the immune response to foreign microorganisms. Like all cells, lymphocytes have a membrane, a lipid bilayer, that envelops the content of the cell. Proteins attached to the cell

Anti-CD20 treatment shows changes not only in B-lymphocytes but also in T-subpopulations

In renal pathology, Rituximab has been proven to be useful in the treatment of some primary glomerulopathies, vasculitis with renal involvement, severe lupus with kidney disease, and especially in renal transplantation, where it is applied during the

Epstein Barr Virus (EBV) infection empowers B lymphocytes for autoimmunity

The human body is under constant threat of foreign invaders (bacteria, viruses, parasites) that can cause infectious diseases. The reason why this often does not occur is the immune system, a complex collection of molecules and cells

STAT3: The double edged molecular sword in Chronic Lymphocytic Leukemia cells

The common denominator of different types of cancers is an ever expanding clone that originates from a single cell. In acute leukemia the clonal expansion may be very rapid and the clone double its size sometimes within

Fine tuning of inflammation is a key to successful limb regeneration

Complete regeneration of appendages after amputation in certain fish and amphibians has long served as a useful model for analyzing why regeneration is unsuccessful in most mammalian organs. Recent work with zebrafish, frog tadpoles, salamanders, reviewed in

From the gut to the eye: commensal microbes as potential triggers of autoimmune uveitis

Autoimmune uveitis is a group of inflammatory diseases that affect the retina of the eye and related tissues and constitute a major cause of human blindness. It is believed that the disease is triggered by the activation

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

In people diagnosed with malignant brain tumors, the prescribed treatment is often radiation and chemotherapy; however, these treatments severely affect the immune system, increasing the chance of early death. Radiation in particular has been known to cause

Caged hens with unusual white blood cells

Animal welfare and egg supply sustainability issues are now top priorities. Currently, most eggs are from caged hens whose welfare is a question. To address the issue, microscopic data from blood counts of hens in three cage