Tag Archives: macrophages
Satiated macrophages produce interferon-beta to orchestrate the resolution of bacterial infection
Acute inflammation is a localized, self-limited host defense mechanism against invading microorganism and tissue injury. Rapid recruitment of white blood cells called neutrophils (polymorphonuclear neutrophil granulocytes) from the blood to the site of infection or injury is
Skewed signaling through RAGE strength the tumor growth-promoting activities of M2 macrophages
Tumors are complex tissues composed by both non-cellular components, mainly matrix proteins, and different stromal cell types, which are under an active cross talk with tumor cells. Tumor-associated macrophages (TAMs) are the major leukocyte population among the
Apple cider vinegar can help clear bacteria and yeast infections; a natural cure
Antibiotic resistance poses a major health issue worldwide. There has never been a greater need for new anti-microbials which are natural, active on multiple organisms and ideally beneficial to the patient. Bacteria such as E-Coli, Staphylococcus aureus
Macrophages in atherosclerosis; the good, the bad and the foamy?
Atherosclerosis is a chronic inflammatory condition in which arteries are narrowed due to the deposition of plaque material to the artery walls. This narrowing can give rise to other cardiovascular events like thrombosis or a stroke. One
The mechanisms of MCP-1 production in tumor microenvironments: Tumor cells are not home alone
When you look at tumors, you may think they are composed of 100% tumor cells. The fact is that tumor tissues contain not only tumor cells but also a variety of non-tumor stromal cells, including fibroblasts, endothelial
Contribution of EphA2 to effective transplantation of macrophages/monocytes into the spleen
The spleen is formed by the white pulp and red pulp. The former is subdivided into the T-cell zone and the B-cell follicles, and the latter into the splenic sinus and the cord. The spleen reacts immunologically
Improving the innate immune response to S. aureus
MRSA, which stands for methicillin-resistant Staphylococcus aureus, is a bacterium that poses a significant health threat. MRSA lives on common surfaces and parts of the body, including the skin and nose. Although MRSA does not always cause
Acute immune responses in the brain differ from responses in blood
Immune cells of the brain called microglia, appear to have been adapted to their vulnerable environment. They react less destructive to danger signals than their counterparts in the blood. Microglia are the resident macrophages of the central
Abolition of mitochondrial substrate-level phosphorylation by itaconic acid
Macrophages are cells of the immune defence system. When they sense the presence of bacteria, one of their genes -called ‘Irg1’- switches on. As a consequence of this, macrophages start to produce and secrete a substance called
