Tag Archives: manganese

TMEM165; The Bermuda triangle of glycosylation and Golgi Mn homeostasis

During evolution, eukaryotic cells have acquired a complex network of endomembranes delimiting distinct organelles with specific cellular functions. In mammals, the rough endoplasmic reticulum (ER) and the Golgi apparatus are two key organelles of the secretory pathway

Getting metals into mitochondria

Metallurgy and the mitochondrion.

Scientists consider mitochondria, an organelle within cells, as a power plant. But mitochondria are also a site for metallurgy. There iron enters heme, the compound that binds oxygen in hemoglobin and certain other proteins, or helps form

A novel approach to characterizing the type of three-factorial combined toxicity

We carried out an experiment in which outbred white rats were subjected to repeated injections with water solutions of either one of the toxics (Mn, Ni or Cr salts) in doses isoeffective in respect to the lethal