Tag Archives: mare

The immunomodulatory enzyme IDO: Expression in the uterus of mares?

Detection of IDO protein in the equine endometrium by immunohistochemistry

IDO modulates immune responses. The enzyme indoleamine 2,3-dioxygenase 1 (IDO) degrades tryptophan. This amino acid is required for immune defences against pathogens, but also stimulates pathogen growth. Its degradation inhibits effector lymphocytes and retards pathogen proliferation. Thus,