Tag Archives: melanoma
Genital melanoma or genital nevus? Molecular answers to a sensitive question
Melanomas arising in the genital region of women are rare although they are the second most common type of cancer in this area. They occur more frequently in women after menopause and tend to be aggressive because
Breslow thickness measurements of melanomas around AJCC staging cut-off points
Melanoma is an aggressive and potentially fatal type of skin cancer. Once a suspected melanoma has been cut out, a pathologist will look at it under a microscope to confirm the diagnosis and measure its “Breslow thickness”.
BRAF inhibitor and interferon alpha combination for melanoma treatment
In recent years approval has been granted to many therapeutic agents for the treatment of patients with metastatic melanoma. They include small molecule inhibitors, such as the selective inhibitors of the mutant BRAF (BRAF-I) or of MEK (MEK-I), and
Keeping Score: dermoscopy for the diagnosis of melanocytic lesions
Among people at high risk for melanoma, skin cancer screening is valuable for early detection of a new malignant melanoma. When dermatologists identify a suspicious lesion, a biopsy is performed and the removed skin sample is sent
Effectiveness of an Internet intervention to decrease young adults’ risk for skin cancer
Every year, almost five million Americans are diagnosed with skin cancer. Though many think of cancer as being an issue for older people, melanoma is the second most diagnosed cancer in adults aged 20-39. This is in
Evaluating methods for detecting deadly skin cancers
Melanoma is a rare, but potentially deadly, type of skin cancer that develops in skin cells called melanocytes, which are responsible for producing the pigment in your skin. According to the American Cancer Society, the probability of
The genetic secrets of Uveal Melanoma
Uveal melanoma (UM) is the most common primary cancer occurring in the eyes of adults, with 1/100,000 new cases per year in the Western world. Most patients are between 60 and 65 years old. Although it is a
Major amputation in the management of advanced limb melanoma
Melanoma is an aggressive type of skin cancer that can recur at the original excision site or spread to nearby areas of the body (called “in-transit” metastases), to the lymph nodes that drain that region and/or to
The surgeon general should say that indoor tanning causes skin cancer
It is a widely accepted fact that smoking causes lung cancer. This dates back to 1964, when the Surgeon General’s report clearly acknowledged this link. Fifty years later, the Acting Surgeon General, Dr. Lushniak, was asked to
Using university-sponsored debit cards for indoor tanning services: an update
Numerous studies have established a link between indoor tanning bed use and increased risk for skin cancer. In fact, those who begin using tanning beds before the age of 35 increase their risk for melanoma, the deadliest
CITED1 is a potential therapeutic target for metastatic melanoma
Cancer kills over 8 million people every year. What makes it so deadly is its ability to spread from the organ where it originates to the rest of the body, a process known as metastasis. Even though
Comparing skin research funding with skin disease burden
Distributing funding dollars to research is an important and daunting task. While many factors influence research-funding decisions, establishing a transparent, priority-setting system is paramount. This is particularly important for the National Institutes of Health, which invests over
Palpable melanoma groin lymph node metastases
Melanoma is the most lethal type of skin cancer. In 2012 232,130 persons were diagnosed worldwide, and 55,488 estimated deaths occurred due to melanoma. Patients who present with a palpable lymph node metastasis in the groin area
