Tag Archives: pain
Information of nociceptive stimuli given to the periphery is transmitted through the dorsal root to the superficial spinal dorsal horn, and then flows to the primary-sensory area of the cerebrum through the brainstem and thalamus, causing pain
Acute pain evoked by tissue injury makes biologic sense and can be explained mechanistically in great detail. It is much more difficult to understand why pain so often persists after healing of an injury, or even arises
There are indications that pain perception is altered in patients with obesity, which complicates postoperative pain treatment. An essential part for adequate pain treatment is the capacity of the patient to grade pain. Methods Forty-one patients with
Serotonin and noradrenaline reuptake inhibitor (SNRI) for chronic musculoskeletal pain may be a red herring?
Dysfunction in the central serotonin and noradrenaline systems cause not only depression but also increased pain sensitivity. Many animal studies indicated that lumbar-intrathecal administration of serotonin and noradrenaline reuptake inhibitor (SNRI) could ameliorate the pain sensitivity which
Chronic pain affects 100 million US adults and with costs exceeding $500 billion per year. Fibromyalgia (FM) is a prevalent chronic pain disorder characterized by widespread pain, fatigue, anxiety and depression, and problems with memory and concentration.
As people get older, lower back and leg pain is a common and often debilitating problem, preventing simple tasks including walking. Unfortunately it is unavoidable because of simple wear-and-tear of the discs and joints that make up
Neuropathic pain in small-fiber neuropathy was traditionally considered a consequence of injury to nociceptors and sensitization. An alternative view has also been put forward: there may be a loss of the neuronal analgesic control system, paralleling the
In the last couple of years, some fascinating abilities of the immune system have emerged: The immune system is tightly interconnected with the nervous system, and can directly affect how the brain functions, and how a person
Our article “Stress is not pain” was a critique on a study by Elwood & Adams who exposed crabs to electric shocks and concluded that their study ‘. . .fulfils the criteria expected of a pain experience’.
In the central nervous system, signals are sent through brain pathways using neurotransmitters, the chemical messengers of our brain. The strength and duration of these messages are governed by the concentration of neurotransmitters in the synapses between
In Australia and elsewhere, older people living in the community use complementary medicines (CM) to manage the symptoms of chronic illnesses, especially pain, and to supplement ‘conventional’ medical treatments for the same conditions. The bulk of CM
Runners, bicyclists, and many other active individuals who experience pain along the lateral side of their knee joint are often diagnosed as having iliotibial band syndrome or iliotibial band friction syndrome. This problem is attributed to a
Glucosamine reduces the need for pain medications in osteoarthritis, but the correct formulation is essential
For osteoarthritis, drugs that can delay disease progression have the potential to reduce the need for additional pain medications. But be careful which drug you chose: this effect is only shown with the prescription patented crystalline glucosamine
A lobectomy is the standard operation for removal of a lung cancer. Traditionally, it is performed through a large incision (approximately 15 cm or 6 inches) at the side of the chest. This incision, termed a thoracotomy,
Neuropathic pain (NP) is caused by the damage of the nervous system and one of the most common types of intractable pain. It is often severe, persistent, and refractory to available therapies. Although various analgesic has been