Tag Archives: Parkinson

GSK-3 beta: a therapeutic target for Parkinson’s disease

Parkinson’s disease

Neurogenesis is a process of birth of newborn neurons from neural stem cells (NSCs). It is a complex, multistep process which involves NSC proliferation, differentiation, migration, maturation and integration of newborn neurons into existing neuronal circuitry. Continuous

Dementia with Lewy bodies and Parkinson’s disease-dementia: Current perspectives

Dementia with Lewy bodies (DLB) and Parkinson’s disease-dementia (PDD) are two closely related major neurocognitive disorders with Lewy bodies of unknown etiology. Both disorders show notable overlap in their clinical presentation, pathological features, biochemistry, and genetic risk

How does Parkinson’s disease gets from your gut to your head?

Parkinson’s disease (PD) is defined as a movement disorder, characterized by a symptomatic phase of motor disturbances such as tremor and slow movements resulting from the severe degeneration of dopaminergic neurons of the substantia nigra pars compacta

Is Metformin a new risk factor for Parkinson`s disease?

Parkinson’s disease is a neurodegenerative disorder that takes place when the neurons of the substantia nigra, a brain structure involved in the movement control, die. This leads to several symptoms including motor and cognitive dysfunctions, progressive loss

22q11.2 deletion syndrome diagnosed in a young patient presenting with Parkinson disease

Chromosome 22q11.2 deletion syndrome (22q11.2DS), also called DiGeorge syndrome, is a fairly common genetic syndrome. In most cases, the diagnosis is made at birth or early in childhood as the most common features of the syndrome –

Parkinson’s alpha-synuclein assembles in the disease prone stable dimers

The self – assembly of proteins into amyloid – type aggregates is a widespread phenomenon associated with many neurodegenerative diseases, including Parkinson’s disease (PD). According to the current model for PD, the aggregation of alpha-Synuclein (α-Syn) and

Antidepressants associated with falls in Parkinson’s patients

Parkinson’s disease is a progressive neurological disorder that affects mobility and is commonly characterized, in advanced stages of the disease, by instability and falls. Falls are a major reason for hospitalization in Parkinson’s patients and may lead