Tag Archives: Parkinson’s

Taking medicines the right way: what do people with Parkinson’s do?

Many people with Parkinson’s have problems swallowing, but they need to take many medicines to lead an independent life. It is more important for people with Parkinson’s to take their medicines on time compared with other patient

Parkinson disease: a tale of three neurotransmitters

The progressive loss of dopaminergic innervation of the basal ganglia, in particular of the dorsal striatum (putamen) is responsible for the motor signs of Parkinson disease such as bradykinesia, rigidity and loss of postural reflexes. Present therapies

Is Metformin a new risk factor for Parkinson`s disease?

Parkinson’s disease is a neurodegenerative disorder that takes place when the neurons of the substantia nigra, a brain structure involved in the movement control, die. This leads to several symptoms including motor and cognitive dysfunctions, progressive loss

The “other” concussion: spinal cord concussion

It was a breezy Sunday afternoon at a football game and the crowd falls silent as they watch the star running back lie motionless after a tackle. The medical team rushed over; the player is conscious and

Parkinsonism Hyperpyrexia Syndrome and Deep Brain Stimulation

Deep Brain Stimulation of the subthalamic nuclei (STN-DBS) represents one of the most effective treatments in patients with Parkinson’s disease (PD) with unsatisfactory response to pharmacological therapy. STN-DBS is a neurosurgical approach based on the implantation of

Stem cell therapy for Parkinson’s disease

Parkinson’s disease is one of the most common neurodegenerative diseases of the central nervous system. Its main symptoms are motor disturbances such as tremors, rigidity and slowing of movements; although patients may also suffer from sleep disorders,

The binding of mGluR4 targeting drugs could help the finding novel treatments for PD

One of the key features of drugs is an ability to find the corresponding target molecule (eg. protein) from the body. The target protein has unique structural sites that could be loaded with specific chemicals (drugs). The

New effective treatments for Alzheimer and Parkinson’s disease

Alzheimer and Parkinson’s disease are the most common neurodegenerative disorders. As people are getting older than in previous generations, the number of people who are affected has increased. Unfortunately, there is no cure for these diseases. The

Uncovering mechanisms underlying Parkinson’s disease pathology

Parkinson’s Disease (PD) is a severely debilitating motor disorder characterized by loss of dopaminergic neurons and an increase of α-synuclein in a brain region known as the substantia nigra pars compacta (SNpc). Although much progress has been

Natural history of multiple system atrophy in USA

Multiple system atrophy (MSA) is a rare, fatal brain disorder exhibiting a combination of parkinsonism and/or cerebellar gait unsteadiness and autonomic failure. Autonomic failure, manifest as orthostatic hypotension, severe constipation and urinary incontinence or retention, as well

Transplanted cells reveal potential for functional neural regeneration

Patients suffering from spinal cord injury and from neurodegenerative disorders such as Parkinson’s disease, amyotrophic lateral sclerosis (Lou Gehrig’s disease) and multiple sclerosis have high hopes for cell transplantation therapy. Successful transplantation depends on the donor cells