Tag Archives: patient
What treatment is really medically and economically desirable for chronic hepatitis C patients with treatment failure after 8-week glecaprevir/pibrentasvir in Japan?
Currently, direct-acting agent (DAA) therapies have high efficacy and safety and are the main strategy to eliminate hepatitis C virus (HCV) worldwide. Some DAA therapies are also effective for HCV-infected patients who have experienced prior DAA failure.
Up to 12% of the U.S. population will be diagnosed with a thyroid condition. Because thyroid hormones affect every cell in the body, hypo- (low) and hyper-(high) thyroidism can be difficult to distinguish from other medical conditions.
Posted by Anna Nadiryan embryologist, cell biologist, medical writer This story is told by Shaun Lawrence from the UK, who was diagnosed with relapsing-remitting multiple sclerosis in 2009. His right leg was aching so much that he
Each year, over four million people go to U.S. Emergency Departments (ED) after a motor vehicle crash (MVC). Although the vast majority of patients are sent home without any serious injuries, many will experience aches and pains
An integrated genomics approach for identifying breast cancer patients with highly aggressive tumors
Breast cancer is the most common cancer in women with over 2 million new cases worldwide in 2018. Three kinds of receptors are usually found on the surface of breast cancer cells: a receptor for female hormone
The healthy neighborhoods healthy families initiative: A zip code should not determine a child’s health
Published in the journal Pediatrics, researchers from Nationwide Children’s Hospital presented a case study for treating a neighborhood as a patient. Neighborhood effect syndrome, characterized by symptoms of extreme poverty including housing insecurity, racial segregation, trauma, violence,
More and more countries have been implementing chronic care programs, such as the Chronic Care Model (CCM) to manage non-acute conditions of diseases in a more effective and less expensive way. Among the CCM components there are
Pulmonary arteriovenous malformations (PAVM) are congenital vascular communications in the lungs. They act as shunts so that the blood running through these malformations is not oxygenated or filtered (Fig. 1). These patients will typically have dyspnea on
Nailfold microangiopathy in dermatomyositis and systemic sclerosis: what is different in long term follow-up?
Dermatomyositis (DM) is a chronic inflammatory disorder involving mainly the skin and muscles. Systemic Sclerosis (SSc) is an autoimmune rheumatic disease of unknown etiology characterized by vascular alterations and progressive tissue fibrosis of multiple organs. Peripheral microangiopathy
Once considered prohibitive, kidney transplantation in HIV (+) recipients is achieving outcomes similar to comparable recipients without HIV. These successes are possible because of incremental improvements in care that resulted from lessons learned from the last two
B-cell lymphomas are a heterogeneous group of malignancies originating from B lymphocytes. Modern day chemotherapy is effective in inducing disease remission in a large percentage of patients for most of the subtypes. Some of these subtypes, the
Can “low calorie”-oil enhance the secretion of incretin hormones with beneficial effects on diabetic patients?
When the human body digests dietary fat (triacylglycerol), hormones from the intestine called incretins are released from the small intestine. These hormones stimulate insulin release and inhibit food intake. The mechanism for the fat-induced incretin release involves
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that damages motor neurons. As the disease progresses, patients gradually loose exercise capacity. Finally, they die due to the lack of breathability. No effective therapy was found for ALS
Sliding esophagoplasty. Can esophagectomy be avoided in esophageal obstruction due to huge thoracic aortic aneurysm?
Thoracic aortic aneurysm is a serious vascular disease which usually requires surgical aortic graft replacement. In recent years, endovascular stent placement proved a mini-invasive alternative to be used safely in properly selected instances particularly in subjects considered
The progressive loss of dopaminergic innervation of the basal ganglia, in particular of the dorsal striatum (putamen) is responsible for the motor signs of Parkinson disease such as bradykinesia, rigidity and loss of postural reflexes. Present therapies
Heart disease is a leading cause of death worldwide. Heart surgeries saves thousands of lives a year but can be lengthy and complex. During surgery, many patients require prolonged periods of intubation and coronary bypass (mechanical support
Pharmaceutical compounding is the preparation of unlicensed medicines in order to meet specific patient needs that do not have a licensed (commercial) medicine available on the market. Especially for patients with rare diseases it is complementary when
The word “cure” for breast or any other type of cancer might be unfair to a patient since this will give the individual a false sense of comfort. The misuse of `cure’ is evident in breast cancer