Tag Archives: patients
How PET ameliorates 90-Yttrium therapy in inoperable liver cancer patients?
Increased synthesis of blood vessels and blood supply are essential characteristics of a tumor to secure nutrient delivery and growth. One of the treatment options for inoperable liver cancer (hepatocellular carcinoma, HCC) is to apply a form of
Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients
Type 2 diabetics are at increased risk of cancer in part because of increased insulin in the blood from insulin resistance. Insulin and its related growth factor IGF-1 can stimulate cell growth through the Ras-Raf-MEK-ERK or the
Insight into the needs of thyroid cancer patients before surgery
The thyroid is a butterfly-shaped gland in the neck below the Adam’s apple. It produces hormones that help influence our metabolism and normal development. Over the last 30 years, the number of new thyroid cancer diagnoses has
An integrated genomics approach for identifying breast cancer patients with highly aggressive tumors
Breast cancer is the most common cancer in women with over 2 million new cases worldwide in 2018. Three kinds of receptors are usually found on the surface of breast cancer cells: a receptor for female hormone
Circulating fibrocytes as possible new target of abatacept effect in systemic sclerosis patients
Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by microvascular and immune response alterations followed by a progressive fibrosis, which is the consequence of an excessive production and deposition of extracellular matrix molecules, primarily fibronectin
Nailfold microangiopathy in dermatomyositis and systemic sclerosis: what is different in long term follow-up?
Dermatomyositis (DM) is a chronic inflammatory disorder involving mainly the skin and muscles. Systemic Sclerosis (SSc) is an autoimmune rheumatic disease of unknown etiology characterized by vascular alterations and progressive tissue fibrosis of multiple organs. Peripheral microangiopathy
Analysis of serum biomarkers and their correlation with pain and quality of life in the rare disease alkaptonuria
Alkaptonuria (AKU) is an ultra-rare disease causing an early onset, chronically debilitating spondylo-arthropathy due to deposition of an ochronotic pigment in joints and spine, which causes severe pain and greatly reduces patients’ quality of life. Despite an
Routine imaging in patients with follicular lymphoma in remission
B-cell lymphomas are a heterogeneous group of malignancies originating from B lymphocytes. Modern day chemotherapy is effective in inducing disease remission in a large percentage of patients for most of the subtypes. Some of these subtypes, the
Got blood!
Blood has been recognized as a life giving force from time immemorial. The first recorded attempt at human to human transfusion was recorded in 1492 when Pope Innocent VII succumbed in an attempt at a transfusion. Successful
Methadone and quality of life: high, low or adjusted doses?
The usefulness of methadone in treating opiate addiction is unquestionable. It is a simple, clean and cheap treatment without any significant side effects. In recent decades, many institutions have written guides and have formulated recommendations advising the
Who will speak for me?
People generally don’t like to think about how their life may end and few consider the possibility of dying in a hospital intensive care environment connected to tubes and monitors where they are unable to express their
Explore care seeking behavior of older adults with hip fracture in Odisha, India
Hip fractures commonly occur in adults over 50 years mostly due to simple falls. Rough estimates suggest 600,000 adults suffer hip fracture injury annually in India. It is expected to rise in coming years as the population
Prognostic value of trans-thoracic echocardiography in patients with acute stroke and atrial fibrillation
Currently, ischemic stroke (which occurs when a blood vessel carrying blood to the brain is blocked) in patients with atrial fibrillation (AF), an abnormal heart rhythm characterized by rapid and irregular beating, can be successfully prevented with
A simple calculation using routine blood test results can identify eosinophilic asthma patients
Complete blood count (CBC) with differential, a standard test that enumerates different types of white cells in peripheral blood, is often performed during routine patient visits in clinics and hospitals. The test can be used to differentiate
Heart disease in cancer patients (onco-cardiology / cardio-oncology)
In the United States, heart disease and cancer have been the 2 leading causes of death from 1935 through 2013. In 2010, both diseases accounted for almost half of all deaths in the U.S. Notwithstanding, much success
Parkinson disease and duodenal levodopa infusion: why patients withdraw the treatment?
Parkinson disease is a chronic and progressive movement disorder associated to degeneration of neurons in the brain, particularly in a region called substantia nigra. These neurons produce dopamine, a neural transmitter that is involved in the control
Understanding the rare disease alkaptonuria: the role of oxidative stress, inflammation and amyloidosis
Alkaptonuria (AKU) is an ultra-rare disease that was recognized among the first inborn errors of metabolism. In AKU, an altered activity of the enzyme homogentisate 1,2-dioxygenase (HGD) occurring upon gene mutation lead to a defective metabolism of
Physical activity helps to reduce cognitive symptoms for dementia patients
Dementia is a clinical syndrome characterized by cognitive symptoms, which lead to disruptions in many aspects of daily life. The most common type of dementia is Alzheimer’s disease, which affects 5.3 million people in the United States
A new water-filled channel that transports metabolites of peroxisomes
Peroxisomes are the detoxifier of almost all nucleated cells. Their name was given in respect to their capability of eliminating reactive oxygen species like hydrogen peroxide. As round-shaped membrane enclosed vesicles, they can have variable sizes from
