Duodenal neuroendocrine neoplasms (dNENs) are heterogeneous tumors and represent up to 3% of all duodenal tumors and 2–3% of all gastrointestinal tumors. Despite clear differences, dNENs have been always treated together with either gastric neuroendocrine tumors or,
Total hip replacement (THR) is a successful procedure to treat end-stage hip osteoarthritis. The procedure is increasingly performed in adults of working age, who often wish to return to highly demanding activities, including a return to sports
Chronic and Polypathological patients (PP) account for a significant percentage both in primary care and in hospital setting. This has led to an increased interest in finding a prognostic survival index in patients with chronic diseases affecting
Cancer is an age associated disease. In Western countries with people having longer life expectancies than e.g. 100 years ago, this means at present that 1-2% of those individuals are confronted with the diagnosis of leukemia during
Choosing the optimal anticancer treatment for each patient requires proper disease staging. Staging is usually assessed according to the TNM system: tumour size (T), number of nearby lymph nodes affected (N), and metastasis, or spread to other
Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk
Influenza is a viral infectious disease that afflicts millions of people every year with fatalities of thousands; sometimes significantly more when it emerges in a pandemic form. The Spanish Flu of 1918 was probably the most severe