Tag Archives: prostate

Turning on neuronal gene programs in prostate cancer cells

AoS. Turning on neuronal gene programs in prostate cancer cells

Cancer of the prostate gland is a common malignancy afflicting males worldwide. This cancer is the second deadliest amongst male in United States, with most of the mortality resulting from aggressive, advanced stage, metastatic disease. Prostate cancer

Prostate volume estimation: is there need for a change in the standard method?

AoS. Prostate Volume Estimation.

As men age, prostate enlargement often leads to complications such as obstruction of the bladder neck and urinary retention with potential consequences on the kidney. Therefore, knowledge of prostate volume is required to help clinicians effectively manage

Harbinger of increased prostate cancer risk: The effect of decreased prostate cancer screening

Harbinger of Increased Prostate Cancer Risk. Atlas of Science

Since the introduction of prostate-specific antigen (PSA) as a blood test in 1992, the number of men diagnosed with prostate cancer increased dramatically. Because PSA detects men who are asymptomatic two things occurred. First, many of the

Enrichment, quantification and glycan analysis of prostate cancer oncomarker in a single step

In recent decades, there is an increasing trend in prostate cancer occurrence and mortality worldwide, caused partly by a more available diagnostics, prolonged life period but also increased risk factors present in the environment. Most commonly, age

Fasting blood glucose and prostate cancer: A meta-analysis of dose-response

Prostate cancer (PCa) is the most common cancer, and third leading cause of cancer deaths, in American men. So far, only a few well-established risk factors, including ageing and being racially black, are thought to be associated

Discovery of prostate cancer-specific peptides using bacterial viruses

Prostate cancer is the most common cancer and the third leading cause of cancer death among American men. Although chemotherapy has been widely used for prostate cancer treatment, it is not specific to cancer cells. As a

Prostate-specific antigen 1.5: The new screening protocol

Prostate cancer is the leading cause of cancer-related death in American men. Tragically, once the disease is spread beyond the prostate gland, therapies become very limited and survival is poor. Like other cancers, prostate cancer can recur

Focal salvage for radiorecurrent prostate cancer

Patients primarily treated with radiotherapy for prostate cancer can get a recurrence. The tumour then regrows. Often this is a localised process and the tumour has not spread to other parts of the body. Therefore, these patients

Three dimensional quality assurance protocol for thoracic and genitourinary radiation therapy

After cancer diagnosis one treatment option is the use of external radiation. As the radiation traverses the patient it deposits most of its energy in the tumor, which causes irreparable damage to the cancer cells. One type

Ultrasensitive detection and glycan analysis of a prostate cancer biomarker

In recent years we have seen an increased frequency of diagnosed prostate cancer (PCa) cases accompanied with an enhanced mortality worldwide. Symptoms of an early-stage PCa can be mild or even absent, thus there is an urgent

Rising from obscurity: 11β-hydroxy-androstenedione under the spotlight

Steroid hormones are small molecules that act as messengers in our bodies, regulating normal development and impacting on disease. These hormones are produced from cholesterol by the actions of enzymes− proteins which change cholesterol to form new

The protective role of estrogens in prostate cancer and its relationship with the SCF/c-KIT system

Prostate Cancer (PCa) is the most common oncological disorder in men worldwide, mainly affecting individuals over the age of 50. Therefore, the population aging and the improved expectancy of life have been contributing to the increased incidence

Regucalcin controls prostate cell proliferation and glycolytic metabolism

Regucalcin (RGN) is a protein with multiple functions and facets, which seems to play an important role in tissue cell homeostasis by regulating the equilibrium between cell survival/proliferation and death, and also in the control of cell