Tag Archives: repair
Defects in mismatch repair increase cancer risk and influence treatment selection
Microsatellites are formed by 1-6 nucleotide base pairs that are repeated in direct order 5-50 times. Repetitive DNA including microsatellites are mainly present in non-coding DNA regions that occupy more than 97% of the nuclear DNA. They
A molecular passport authorizes intracellular travel for a potential cancer therapy antibody
Whether from external environmental factors or spontaneous intracellular processes, the DNA in our cells is under constant bombardment by DNA damage. Because unrepaired DNA damage can cause cell death, our cells have evolved vital mechanisms to repair
A DNA repair gene, OGG1, polymorphism affects relapse risk of acute myeloid leukemia
Approximately 80% of acute myeloid leukemia (AML) patients can achieve complete remission, but around half of them relapse within five years. Defining the mechanism of relapse is essential to improve the prognosis of AML. Recently, a clonal
Smaller cut, same result
The mitral valve is one of the four cardiac valves. It sits in the left side of the heart where it serves to prevent backflow of blood from the pumping chamber of the heart (ventricle) and the
Bioresorbable Mg implants modified by nanostructured merwinite/PEO coating for hard tissue repairs
Metallic biomaterials for example stainless steel, titanium, and cobalt – based alloys are using as permanent bone implant materials for orthopedic applications. However, they have some problems : 1 ) the difference between the mechanical properties of
Use of an in vitro model of blastema tissue from Rabbit pinna
Rabbit ear wound repair is an accepted model for studies of tissue regeneration, leading to scar less wound repair. It is believed that a specific tissue, blastema, is responsible for such interesting capacity of tissue regeneration. To
