Tag Archives: scarring limb
Tail regeneration in lizard is driven by key genes of the Wnt-pathway
The importance of lizards as models to analyze the process of organ regeneration is relevant since, differently from the classical amphibian models, these vertebrates are amniotes adapted to the terrestrial environment, therefore closer to mammals and humans.
Immune damage of Apical Epidermal Cap impedes limb regeneration in frog
The evolution of the immune system in terrestrial vertebrates has allowed a high efficiency in the protection against mutated and cancer cells, foreign substances and microbes. Immune cells however become fully immunocompetent only late during development or
Key genes for amniote organ regeneration detected in lizard transcriptomes shed new hope for limb regeneration in humans
While in water-adapted vertebrates (anamniotes: fish and amphibians) organ regeneration is relevant or outstanding, including in fins or limbs, in fully terrestrial vertebrates (amniotes: reptiles, birds and mammals) regeneration is absent or rare. Aside numerous anatomical and
