Tag Archives: steatohepatitis

The lysosomal enzyme cathepsin D as novel therapeutic target for non-alcoholic steatohepatitis

The decrease in physical activity combined with increased caloric intake has led us to a global obesity epidemic. Obese patients can develop metabolic syndrome (MetS), which is a term used to assess the risk of a patient

The protein p62 helps liver cancer-initiating cells survive

The most common form of adult liver cancer is hepatocellular carcinoma (HCC), which is the third-leading cause of cancer deaths worldwide. HCC arises from persistent liver inflammation related to hepatitis B or C infection, alcohol consumption, or

Melatonin’s role preventing steatohepatitis and improving liver transplantation results

Melatonin (N-acetyl-5-methoxytryptamine) is produced by the pineal gland as well as by many other organs including ovary, testes, bone marrow, gut, placenta, and liver. This molecule is both a biological rhythm regulator and an important component of