Tag Archives: steroid
Tumor regression in a high-mortality mouse pancreatic cancer (xenograft) model with aminosteroid RM-581
Pancreatic cancer is classified as a high-mortality cancer with a five-year relative survival rate of only 9%. Although most cancer type survival rates have improved over the past decades, pancreatic cancer morbidity has been stable, which illustrates
Milk and beef: Do production enhancing hormones pose a health risk?
After World War II, a sharp increase in demand for beef and dairy products, coupled with a burgeoning veterinary pharmaceutical industry, led to a number of changes in animal husbandry, including a reliance upon exogenous hormones to
Treatment of experimental eye inflammation with a single subconjunctival injection of liposomal steroid
Non-infectious anterior uveitis is an inflammatory condition in the front of the eye that can potentially lead to blindness. The current gold standard for treatment is with steroid eyedrops. However, this treatment has several disadvantages. Very little
Host factors, the “Simon Says” for microbial biofilms
Microbes change their behavior, i.e., phenotype, in response to environmental clues. Since microbes, e.g. normal flora and pathogens evolved with their respective hosts, being able to recognize host-derived chemical signals provides a distinctive advantage. This is particularly
Steroid hormones regulated the cellular immune response of the crustacean
The endocrine system plays a crucial role in metabolism. Endocrine – secreted materials regulate the growth , development, reproduction, and immune response of organisms. In crustaceans , steroid hormones have been synthesized by feeding cholesterol as the
Allylic oxidation of steroidal olefins
The goal of steroid chemistry is to chemically modify naturally occurring steroids in a way that will alter their biological activity to the benefit of mankind, livestock, and plants. This process can be achieved by adding a
