Tag Archives: therapy
Acute ischemic stroke: Can clinical risk factors exclude more women than men from thrombolysis therapy
Acute ischemic stroke is the physiologic manifestation of lack of perfusion to the brain. This lack of blood flow may be secondary to thrombosis of a large vessel, an embolus from elsewhere that lodges into a smaller
Ultrapure cells for liver research
Worldwide, hepatic fibrosis, cirrhosis and hepatocellular carcinoma cause considerable human suffering and high economic burdens. Causally responsible for the accumulation of excess scar tissue within the diseased liver are hepatic stellate cells (HSCs) representing 5-8% of the
Acting in mechanisms of aging to delay/prevent Alzheimer’s disease
Alzheimer’s disease (AD), a severely debilitating and ultimately fatal brain disorder, affects millions worldwide. To date, clinical efforts to find a cure or adequate treatment have met with dispiriting failure. The disease is now on an ominous
RKIP and YY1: The ‘good’ and the ‘bad’ shields in the protection of cancer spreading and resistance to therapies
Cancer originates from all of the uncorrected mutations occurring in the DNA of the cell that lead to abnormal cell growth. Accordingly, the accumulation of these mutations transforms a normal cell into an “immortal” cancer cell with
Antithrombotic therapy duration after coronary stenting: finding the sweet-spot with a novel clinical risk score
Coronary atherosclerosis is still the principal cause of morbidity and mortality in western countries, by inducing ischemia or infarction of the myocardium. Percutaneous treatment of atherosclerotic lesions is nowadays the most common form of treatment of such
New therapy for the treatment of childhood bone cancer
Cancer in children and young adults is rare, with survival rates being very high, mainly depending on the treatment. The biggest proportion of this diagnosis will be on leukaemia and brain tumours, with just about 3% of
Applying nanopharmacology to obstetrics: A novel targeted drug delivery system for the uterus
Pregnancy is a dangerous period for both the mother and foetus. Being born too early (preterm birth) is the leading cause of death and disease in children <5 years of age, while insufficient uterine contractions during or
Discovery of Bag3-P209L signaling mechanism brings hope for therapeutic options currently in development
Myofibrillar myopathy (MFM) is a group of rare genetic disorders that cause both skeletal and cardiac muscle weakness. Mutations in the Bcl2-associated Athanogene 3 (Bag3) protein, highly expressed in striated muscle, are reported to cause a particularly
Annual Summit on Cell Signaling and Cancer Therapy. Chicago, USA. September 27-28, 2017
Annual Summit on Cell Signaling and Cancer Therapy is bustling to be held at Chicago, USA during September 27-28, 2017 hosted by Conferences Series. Through the theme “To Frame An Admiring Portal For Pioneering Cancer Therapy and
Radiation-induced morphea: an under-recognized complication of breast radiation
Worldwide, breast cancer was the most common new diagnosis and common cause of death in women in 2012. As screening for breast cancer has improved patients are often identified in the early stage of disease and are
ACT for a “self” relieved of the burden of pain
Chronic pain is often defined as any pain lasting more than 3 months, and may arise from an initial injury, an on-going illness, or no clear cause. The change and suffering wrought from chronic pain could fundamentally
Novel approaches to cancer treatment encoded within non-coding RNA
A hallmark of all living organisms is the presence of genetic material within each cell; this material is invariantly composed of a specific class of biological molecules known as the nucleic acids. While the more familiar variety
A New therapy for healing nonunion fractures in patients using self-bone marrow derived mesenchymal
Sometimes a broken bone fail to heal (“nonunion”) and it is necessary to induce the formation of new bone tissue to connect the broken pieces. Investigators from the Instituto Venezolano de Investigaciones Cientificas (IVIC) and orthopedic surgeons
An international team opens new avenues toward PKU therapy
When a baby is born, a simple blood test reveals whether the child has PKU, which is a recessive genetic disorder where the body fails to regulate the amount of phenylalanine (Phe) in blood. Phe is a
Nonadherence to immunosuppressive therapy in kidney transplant recipients
End-stage kidney disease (ESKD) is an increasing worldwide illness that compels patients to accept either dialysis or kidney transplantation that is the best choice because ensures high quality of life. But, living or cadaveric kidney donation is
Nutritional therapy may slow down cirrhosis
One in 400 citizens of western industrialized countries suffers from chronic liver disease or its end-stage, liver cirrhosis. The only definite cure for this is a liver transplant, but the scarcity of organs and required immunosuppression render
Fluorescent carbon dots integrated hydrogels for lung cancer therapy
Cancer is considered as one of the leading cause of death worldwide. Due to the ever changing lifestyle of the modern society, the incidence of cancer is on the rise. Lung cancer is the most frequently diagnosed
The key key to open the door of iPSCs clinical therapy for patients
The discovery of iPSCs is probably one of the most astonishing accomplishments in the beginning of 21st century. This is by 4 early protein factors, the differentiated cells–such as fibroblasts, T and B cells—can return to pluripotent
Prompt resolution of essential drug intolerance
The gut is nowadays seen as a site of cross-talk and interchange between the inner body (supposed to be sterile, namely free of viable harmful bugs) and the outer contaminated world, mainly entering the digestive tract through
Improving nature’s own communication system to fight cancer
Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of
