Tag Archives: tumor microenvironment

The mechanisms of MCP-1 production in tumor microenvironments: Tumor cells are not home alone

When you look at tumors, you may think they are composed of 100% tumor cells. The fact is that tumor tissues contain not only tumor cells but also a variety of non-tumor stromal cells, including fibroblasts, endothelial

Microfluidic tumor models help pre-clinical screening of T cell cancer immunotherapies

Cancer immunotherapy draws upon the patient’s own immune system to recognize and fight the disease. One form of cancer immunotherapy is known as adoptive T cell therapy (ACT) consisting of isolation, genetic manipulation and reinfusion into the

Focusing on non-tumor-derived factors for leukemia therapy

Approximately 10-20 million people worldwide are estimated to be infected with human T-cell leukemia virus type I (HTLV-I), and 1-3% of HTLV-I-infected individuals develop a cancer of CD4+ T lymphocytes in the blood each year.  The retrovirus-associated