Tag Archives: X-ray

Cryo-electron microscopy in drug development

AoS. Cryo-electron microscopy in drug development

Cryo-electron microscopy (cryo-EM) is becoming the method of choice in structure determination of membrane proteins and has great potential for structure-based drug discovery (SBDD). Cryo-EM provides high-resolution structural information of a membrane protein without the need for

Nickel free, built-in nanotubular drug eluting stents

AoS. Ni-free, built-in nanotubular drug eluting stents

Coronary Artery Disease is a common cause of heart failure. Coronary Artery Disease (CAD) is caused by the accumulation of lipids and fats within an injured arteries’ walls and restricts the blood flow to the heart muscle

Imaging metal nanoparticle adsorption on graphene aerogels

AoS. Imaging metal nanoparticle adsorption on graphene aerogels.

The functionalization of porous carbon aerogels and sponge-like materials with metal nanoparticles (NPs) has shown significant promise for several applications, including energy storage and harvesting and environmental remediation. Methods for imaging the internal structure of these porous

Virtual unrolling of damaged historic scrolls from X-ray micro-tomography scans

Virtual Unrolling of Damaged Historic Scrolls. Atlas of Science

For many years there has been limited success in extracting the contents of historical parchments that are so badly damaged by fire, water, etc. that they cannot be opened or unrolled without causing further damage, meaning that

Future trends in high-resolution 3D visualization of individualized neurons in whole tissues using Synchrotron-based X-ray microtomography: a new world to be explored

Future trends in high-resolution 3D. AoS

The understanding of neuron cells as individualized entities has its beginning in the 19th century as a result of the work developed by Santiago Ramon y Cajal on the basis of histological techniques developed by Camillo Golgi. These

Using controlled disorder to probe coexisting quantum orders in NbSe2 superconductor

Using controlled disorder to probe coexisting quantum orders. AoS

Many pure elements and complex compounds become superconducting when their electrical resistance drops to zero below critical temperature, Tc. For more than a century, the race for higher Tc remains one of the most exciting topics in

Mechanical vibrations can indicate if a fracture is healing

Mechanical Vibrations can indicate if a fracture is healing

One of the most critical issues in orthopaedics is the development of a procedure for assessing fracture healing in an objective way and by means of a non-invasive approach, replacing the actual gold standard based on X-rays.

Does body mass index affect how well patients do after meniscus surgery?

Obesity is present in about 38% of adults in the United States, and as many as 67% of patients with knee injuries (including meniscus tears). Some research has shown that obese patients have worse function and more

Mimicking enzymes using artificial proteins

Critical to life on earth is the ability of proteins called enzymes to catalyze a wide range of chemical reactions, such as producing essential molecules by breaking down food in humans, and producing oxygen from water in

The physical entrapment of milk fat in cheese products impacts structure and functionality

Fats are an integral part of many food products, contributing to texture, flavor, and satiety aspects. In general, fats exist as a mixture of both solid and liquid triglycerides, where the solid fraction assembles into crystalline domains

The longest single crystal structure confirmed azaacene derivative: one step forward large conjugation molecules

Organic semiconductors are supposed to be the next generation semiconductors, which shows many great advantages over silicon. For example, their devices are easier and cheaper for fabricating and can be flexible. Their variable molecular structures can be

Significant effect of polyoxometalates on the molecular structures of phosphanegold cluster cations

Gold(I) cluster complexes have attracted much attention owing to their excellent catalytic activity in a broad range of organic reactions. We recently discovered that polyoxometalate (POM ) – mediated clusterization of monomeric phosphanegold(I) complexes results in the

Halogen bonding assembly of an iodide-binding triple helix

Wind turbines, spiral staircases, and springs—these are a few examples of helices in everyday life. The helix is also a reoccurring concept in mythology, spanning many cultures. In biology, helices are both essential and pervasive. Collagen, the

Can Radon radiation become a source of treatment for Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is the most common type of autoimmune disease. It is triggered by a faulty immune system of the body. However, the real cause of the disease is not completely known. The disease affects the

Computational identification of plastic debris in the marine environment

The presence of plastics on the marine environment has several dangerous effects on the aquatic living organisms. Plastics have high chemical stability and are invariant with respect to the degradation agents.  Their accumulation on sea surface produces

Luminescent molecular wires that consist of up to eight copper atoms

Linear multi-atom complexes of Group 11 metals (Cu, Ag, Au) exhibit fascinating luminescence properties that make them highly interesting 1) for the systematic design of molecular wires in nanoelectronics and 2) their application as light-emitting building blocks

Automated chest X-ray screening: can edge map measure the evidence of pulmonary abnormalities?

Among many pulmonary diseases, according to the 2014 WHO report, Tuberculosis (TB) is considered as one of the deadliest communicable diseases. While TB cure rates over 90% have been documented in resource-rich countries, its detection and treatment

Tumor risk from low-dose radiation exposures with the example of dental diagnostic X-ray

It was reported that exposure to dental diagnostic X-rays in oral, dental and maxillofacial care increases the risk of benign tumors (meningioma), but not of malignant brain tumors (glioma). Malignant gliomas grow more rapidly. Meningioma, a benign

An international team opens new avenues toward PKU therapy

When a baby is born, a simple blood test reveals whether the child has PKU, which is a recessive genetic disorder where the body fails to regulate the amount of phenylalanine (Phe) in blood.  Phe is a

Primary care doctor follow up of buckle fractures of the forearm

A buckle fracture of the distal radius (wrist bone) is a very minor fracture and the most common fracture in childhood. A “buckle” fracture occurs when there is a wrinkling of the outer edge of the bone