Tag Archives: organic synthesis

Chemical synthesis of 12-HHT and related metabolites derived from polyunsaturated fatty acids

Collaboration of organic chemistry and biology has successfully developed a new area of research. Science of metabolites derived from polyunsaturated fatty acids by COX or LOX is one of successful examples. These metabolites are chemical mediators that

C-H bond activation by metal carbene

C-H bonds, alongside with C-C bonds, are the most common chemical bonds that constitute organic molecules. C-H bonds are ubiquitous and they are also very stable. The replacement of the hydrogen atom of the C-H bond with