Tag Archives: treatment

An epigenetic treatment strategy puts a brake on alcohol dependence

An Epigenetic Treatment Strategy Puts a Brake on Alcohol Dependence

Alcohol use disorder, commonly known as alcoholism, is a chronic debilitating psychiatric disease that affects >16 million people in the United States. Disease progression of alcoholism cycles through several different stages, characterized by preoccupation or needing to

Treatment of elderly patients with pancreatic cancer

Our publication is about elderly patients’ treatment evaluation for pancreatic cancer in the United States. This is a Surveillance, Epidemiology, and End Results (SEER)-Medicare analysis of patients above age of 65 who have Medicare and were treated

Clostridioides difficile infections: what is new in laboratory diagnosis and clinical treatment

Clostridioides difficile infections (CDI) have become a major economic issue from developing countries as well as from the Western World. Early and accurate diagnosis of CDI allows earlier treatment, which can significantly reduce the morbidity, mortality, medical

Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed

Treatment of autoimmune blistering diseases during pregnancy

Autoimmune Blistering Diseases During Pregnancy

Autoimmune blistering diseases occur when one’s own immune system attacks the skin and mucous membranes (such as your mouth) forming blisters. This group of diseases including pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, and pemphigoid

Prognostic factors for PM/DM-ILD. A dilemma of treatment intensity?

Schematic representation of the predictive prognostic factors for PM/DM-ILD.

Polymyositis (PM) and dermatomyositis (DM) are idiopathic inflammatory myopathies of unknown causes. In PM/DM, interstitial lung disease (ILD) is one of the extramuscular manifestations and the principal cause of death. To improve the prognosis of PM/DM-ILD, it

Inflammatory Bowel Disease: medical vs surgical vs “sociological” treatments

The human gut continuously hosts an excess of white blood cells in its wall thickness, this lingering inflammation serving to protect us from the outer world that uses the gut as an invading pathway. Unchecked gut inflammation

The dichotomy of exosomes in cancer: targets and treatment vehicles

Exosomes are extracellular vesicles released by all cell types that mediate intercellular communication. Exosomes exist in healthy as well as pathological conditions, but it is in cancer research that they are gaining increasing attention. Exosomes released by

The aptamer BC007: for the treatment of “functional autoantibody diseases”. First developed for patients with dilated cardiomyopathy

Autoimmunity is accepted as the origin or amplifier of various diseases. In the mid-1970s, a new class of “so-called” functional autoantibodies that bind to G-protein-coupled receptors (GPCR-AABs) was identified for downstream pathologies. The related “functional autoantibody diseases”

Chagas disease a neglected ills without treatment

Chagas disease (CD) is transmitted by the parasite Trypanosoma cruzi, and was discovered in 1909 by the Brazilian medical doctor named Carlos Chagas. Until today, CD remains a serious public health problem, with more than 7 million

Magnetic stimulation to target auditory verbal hallucinations in schizophrenia

Schizophrenia (SZ) is a severe chronic mental disorder characterized by a range of symptoms, potentially including delusions, confused thinking, and hallucinations. One of the best-known symptoms is auditory verbal hallucination (AVH), also known as “hearing voices”, which

How to optimize pneumonia treatment for the elderly

Can you tell the age of this patient with pneumonia by looking at her chest X-ray (Fig. 1)? Neither can the germ infecting her. And yet there are unique aspects of treatment to know if the patient

How much alcohol is in ketamine`s antidepressant response?

The rapid and robust antidepressant action following a single intravenous sub-narcotic ketamine infusion (usually 0.5 mg/kg over 40 minutes) in the treatment of resistant major depression is unique and encouraging, albeit short-lasting (up to 7 days). Increasing

New therapy for the treatment of childhood bone cancer

Cancer in children and young adults is rare, with survival rates being very high, mainly depending on the treatment. The biggest proportion of this diagnosis will be on leukaemia and brain tumours, with just about 3% of

Physician barriers to evidence-based medicine

In the era of new genetic tests and advanced imaging, much is written on the future of precision medicine, the concept of delivering personalized, evidence-based treatment based on patients’ individual characteristics. Risk prediction models are an excellent

Methadone and quality of life: high, low or adjusted doses?

The usefulness of methadone in treating opiate addiction is unquestionable. It is a simple, clean and cheap treatment without any significant side effects. In recent decades, many institutions have written guides and have formulated recommendations advising the

Gum disease matters!

Periodontal diseases are abnormal processes affecting the gum, mostly gingivits and periodontitis. Gingivitis is an inflammation of the gum, and periodontitis occurs when this inflammation progresses deeper into the gum affecting tooth support. Teeth are anchored to

The importance of clinical endpoints in lymphoma

Lymphomas, or neoplasms of the lymphoid system, include a broad array of cancers. The least aggressive, often called indolent, lymphomas (the most frequent of which is follicular lymphoma, FL) are characterized by their incurability. At the same

What do or should we value in the treatment for psychotic individuals?

Even with the biological approach adopted by mainstream psychiatry, it seems necessary to revitalize interest in the use of psychotherapy in the treatment of psychosis. Supporting this idea,  there are compelling reasons. One of the most important

Uncomplicated type B acute aortic dissection: endovascular repair or best medical treatment?

Patients with uncomplicated type B acute aortic dissection (type B-AAD) are commonly treated with conservative therapy (best medical treatment [BMT]) although the long-term outcome of medical therapy alone is suboptimal, with a reported 30% to 50% mortality