Tag Archives: treatment

Novel drug treatment for human infection with H7N9- avian influenza A

Distribution of Avian Influenza A(H7N9) virus infection in China. AoS

The H7N9 subtype of avian influenza is an enzootic and airborne virus which caused an influenza outbreak in China. Infected individuals mostly worked with poultry, suggesting H7N9 virus-infected poultry as the primary source of human infection. Significantly

Tumor regression in a high-mortality mouse pancreatic cancer (xenograft) model with aminosteroid RM-581

Chemical representation of aminosteroid derivative. Atlas of Science

Pancreatic cancer is classified as a high-mortality cancer with a five-year relative survival rate of only 9%. Although most cancer type survival rates have improved over the past decades, pancreatic cancer morbidity has been stable, which illustrates

Stem cells and stem cells conditioned medium for inflammatory bowel disease treatment

Stem cells. AoS

Inflammatory bowel disease (IBD) is a complex of pathological processes occurring in the intestine. Chemically induced IBD in rodent usually used for study of drug therapy efficacy. Mesenchymal stem cells (MSC) was used as alternative method for

How we can curb deaths from heroin use

Evidence from many countries shows an alarmingly high death rate amongst former prisoners with histories of heroin addiction in the two weeks following their prison release. A heroin overdose is the most common cause of death in

Treatment of experimental eye inflammation with a single subconjunctival injection of liposomal steroid

Treatment of experimental eye inflammation

Non-infectious anterior uveitis is an inflammatory condition in the front of the eye that can potentially lead to blindness. The current gold standard for treatment is with steroid eyedrops.  However, this treatment has several disadvantages. Very little

Inhibitors of intracellular enzymes for treatment of multiple sclerosis

The protein kinase inhibitor imatinib

Lymphocytes are white blood cells that are central in the immune response to foreign microorganisms. Like all cells, lymphocytes have a membrane, a lipid bilayer, that envelops the content of the cell. Proteins attached to the cell

Subjects with gambling-related problems requiring treatment

Subjects with Gambling-Related Problems Requiring Treatment

Gambling disorders affect 0.2–5.3% of adults worldwide, although measurement and prevalence varies according to the screening instruments and methods used, and the availability and accessibility of gambling opportunities. A significant percentage of gamblers develops clinically relevant gambling

Oral corticosteroids on hand to treat the next asthma exacerbation?

Outcome of asthma the years before and after oral corticosteroids were provided to parents for treatment of the next exacerbation.

Asthma exacerbations are a major cause of visits to an emergency room, especially for children. What is an asthma exacerbation? There is general agreement that acute symptoms of asthma become an exacerbation when they are more frequent

An epigenetic treatment strategy puts a brake on alcohol dependence

An Epigenetic Treatment Strategy Puts a Brake on Alcohol Dependence

Alcohol use disorder, commonly known as alcoholism, is a chronic debilitating psychiatric disease that affects >16 million people in the United States. Disease progression of alcoholism cycles through several different stages, characterized by preoccupation or needing to

Treatment of elderly patients with pancreatic cancer

Our publication is about elderly patients’ treatment evaluation for pancreatic cancer in the United States. This is a Surveillance, Epidemiology, and End Results (SEER)-Medicare analysis of patients above age of 65 who have Medicare and were treated

Clostridioides difficile infections: what is new in laboratory diagnosis and clinical treatment

Clostridioides difficile infections (CDI) have become a major economic issue from developing countries as well as from the Western World. Early and accurate diagnosis of CDI allows earlier treatment, which can significantly reduce the morbidity, mortality, medical

Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed

Treatment of autoimmune blistering diseases during pregnancy

Autoimmune Blistering Diseases During Pregnancy

Autoimmune blistering diseases occur when one’s own immune system attacks the skin and mucous membranes (such as your mouth) forming blisters. This group of diseases including pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, and pemphigoid

Prognostic factors for PM/DM-ILD. A dilemma of treatment intensity?

Schematic representation of the predictive prognostic factors for PM/DM-ILD.

Polymyositis (PM) and dermatomyositis (DM) are idiopathic inflammatory myopathies of unknown causes. In PM/DM, interstitial lung disease (ILD) is one of the extramuscular manifestations and the principal cause of death. To improve the prognosis of PM/DM-ILD, it

Inflammatory Bowel Disease: medical vs surgical vs “sociological” treatments

The human gut continuously hosts an excess of white blood cells in its wall thickness, this lingering inflammation serving to protect us from the outer world that uses the gut as an invading pathway. Unchecked gut inflammation

The dichotomy of exosomes in cancer: targets and treatment vehicles

Exosomes are extracellular vesicles released by all cell types that mediate intercellular communication. Exosomes exist in healthy as well as pathological conditions, but it is in cancer research that they are gaining increasing attention. Exosomes released by

The aptamer BC007: for the treatment of “functional autoantibody diseases”. First developed for patients with dilated cardiomyopathy

Autoimmunity is accepted as the origin or amplifier of various diseases. In the mid-1970s, a new class of “so-called” functional autoantibodies that bind to G-protein-coupled receptors (GPCR-AABs) was identified for downstream pathologies. The related “functional autoantibody diseases”

Chagas disease a neglected ills without treatment

Chagas disease (CD) is transmitted by the parasite Trypanosoma cruzi, and was discovered in 1909 by the Brazilian medical doctor named Carlos Chagas. Until today, CD remains a serious public health problem, with more than 7 million

Magnetic stimulation to target auditory verbal hallucinations in schizophrenia

Schizophrenia (SZ) is a severe chronic mental disorder characterized by a range of symptoms, potentially including delusions, confused thinking, and hallucinations. One of the best-known symptoms is auditory verbal hallucination (AVH), also known as “hearing voices”, which

How to optimize pneumonia treatment for the elderly

Can you tell the age of this patient with pneumonia by looking at her chest X-ray (Fig. 1)? Neither can the germ infecting her. And yet there are unique aspects of treatment to know if the patient