Tag Archives: gastrointestinal

Gastrointestinal stromal tumor transition to KIT-independence is enabled by a Cyclin D1 dependent proliferation program

AoS. Gastrointestinal stromal tumor transition to KIT-independence is enabled by a Cyclin D1 dependent proliferation program.

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. GISTs generally contain oncogenic gain-of-function KIT (~85%) or PDGFRA (~5-10%) mutations which are crucial for GIST proliferation and survival, as underscored by the

Molecular mechanisms of gastrointestinal disorders caused by general anesthesia

Nowadays it is impossible to imagine surgery procedures without general anesthesia. From the wide variety of general anaesthetics both intravenous (such as propofol, ketamine, fentanyl etc.) and inhalation anesthetics (such as isoflurane, sevoflurane, desflurane etc.) are some

Bioengineered human pyloric sphincters with functional muscle and nerves

The gastrointestinal (GI) tract is a hollow tube that primarily functions to mediate the digestion of the food that we eat into forms of energy and nutrients that the cells and our body can use. The appropriate