Yearly Archives: 2023
What Planets and Moons Can You See with Astronomy Binoculars?
Astronomy binoculars are a gateway to the cosmos for both amateur stargazers and seasoned astronomers. They blend the convenience of portability with the thrill of celestial discovery. In this expanded guide, we delve into the fascinating world
Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?
Glucocorticoids are medications widely used to treat inflammation and allergies, and in contexts of immunosuppression such as after transplants. They are well-established and safe. The problem is that, when used for a long time, or in high
Galectin-9: A new target for beating atherosclerosis?
Atherosclerosis is a chronic medical condition characterised by the accumulation of fat in the walls of blood vessels, which obstruct the normal flow of oxygen-rich blood and can have severe health consequences. Peripheral arterial disease (PAD) is
Cardiomyocyte Metabolism Research and Cardiogen Peptide
Peptide complex Cardiogen has been hypothesized to function as a bioregulator of cardiovascular function. Fibroblasts, the cells often credited with scar formation and tissue regeneration, are proposed to be the principal targets of Cardiogen in investigations. H-Ala-Glu-Asp-Arg-OH
Naturally occurring peptide may tackle the “root cause” of obesity-related diseases
Obesity typically occurs when a person eats more calories than they need for their daily activity. It results in a build-up of fatty tissue around all organs. In lean people, fat tissues work closely with hormones to
Linking copper, tyrosines and protein aggregation in Alzheimer’s disease
The prevalence of Alzheimer’s disease (AD), the most common cause of dementia nowadays, is expected to increase within the coming years, representing a serious threat for society and the healthcare system. For this reason, a lot of
Improving assessment of arthritis models to better reflect human symptoms of disease
Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to
Systemic therapy in juvenile localized scleroderma
Juvenile localized scleroderma, also known as morphea, is an rare condition, it occurs around 1 in 5000 children, where the skin and the tissues underneath the skin like fat tissue, muscle, tendons, and bone, get inflamed and
Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria?
Progressive Supranuclear Palsy (PSP) is the second most common degenerative parkinsonian syndrome after idiopathic Parkinson’s disease. PSP is a clinically heterogeneous disorder with several clinical variants. The two most common clinical variants are the Richardson (PSP-RS) and
Microbial community assembly and the microbiome revolution
Microbial communities (i.e. groups of potentially interacting microbial populations that co-exist in space and time) most commonly represent complex and highly diverse assortments of microbial populations, each possessing different genomic features that reflect on their specific life
Exploring gap junction networks required for zebrafish skin pattern formation
The study of pattern formation has advanced to a new phase involving channel molecules acting on bioelectric signals, with gap junctions being major relevant factors. Gap junctions are composed of connexin proteins: six connexins form hemichannels/connexons on
The Science Behind Optical Alignment Instruments
Optical alignment is similar to fine-tuning the lenses in your glasses to help you see clearly. It’s a fundamental process in ensuring that optical devices like cameras, microscopes, and equipment used to make computer chips work perfectly.
Social rank recognition is altered in autism spectrum disorder
Humans and many other animals spend their lives in social groups, along with constructing social hierarchy within the groups. Since social hierarchy is a principal determinant for allocation of limited resources for individuals in a group, assessments
Is that possible to prevent parasitic iatrogenic blood bank transmission?
Chagas disease (CD) is neglected tropical disease (NTD) that affects over 6 million people mainly in the poorest areas of Latin America. CD also represents a public health concern in non-endemic areas such as North America, Asia,
Waking a sleeping giant: How increasing Africa’s research output can benefit global cardiovascular health?
Africa is home to 1.4 billion people, of whom 55 million suffer from cardiovascular disease (CVD). Despite this, Africa contributes to only 1.7% of the world’s cardiovascular science. We studied 179 clinical trials led by African researchers
Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation
Since the emergence of immune checkpoint inhibitors (ICIs), cancer immunotherapy has dramatically developed. However, its drawback is the low overall response rate to its therapeutic effect. The efficacy of immunotherapy is suggested to depend on the immune
Sustainable solutions: Tamarind Seed Kernel powder (TKP) adhesive as a green alternative for lignocellulosic composites
The majority of petroleum-based adhesives applied in the wood industry today, particularly formaldehyde-based adhesives. Their application trend is increasing due to their wide availability, superior bonding, durability, and resistance to heat and moisture. However, formaldehyde-based adhesives continuously
Fatigue assessment strategy using Bayesian techniques
The fulfilment of the probabilistic fatigue characterization of materials based on the S-N field requires the definition of the statistical distribution of the percentile curves of the failure probability, interpreted as a simplification, by their confidence bands.
How Studying Earth Science Can Benefit Your Life
Have you ever wondered how our world really works? If so, then the only way to get an in-depth look at the earth and how it works is to study earth science. This is a complex field
Starch fatty acid esters – versatile bio-based thermoplastics
The biopolymer starch is well-known in the kitchen for baking, cooking, and as a component of flour and is available in large quantities. This makes starch interesting as sustainable resource to convert it into biodegradable products to
