Tag Archives: alpha-synuclein

TRIM32 and alpha-synuclein: a novel interplay in the neuronal system

Parkinson’s disease (PD) is the second most common neurodegenerative disease mainly characterised by the progressive loss of nigrostriatal dopaminergic neurons, resulting in a series of motors symptoms and the formation of intracellular inclusions within the cells, known

Parkinson’s alpha-synuclein assembles in the disease prone stable dimers

The self – assembly of proteins into amyloid – type aggregates is a widespread phenomenon associated with many neurodegenerative diseases, including Parkinson’s disease (PD). According to the current model for PD, the aggregation of alpha-Synuclein (α-Syn) and