Tag Archives: bacterium

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this I have used the hepatopancreatocytes of decapod crustaceans as an example, Specifically, I tried

Obligatory intracellular bacterium exploits evolutionarily conserved host signaling pathway to survive

In order to survive, obligately intracellular pathogens exploit host cellular signaling pathways and other cellular processes via molecular interactions between pathogen – secreted “effectors” and host target proteins to reprogram host cell functions.  However, the molecular mechanisms