Tag Archives: breast cancer

Sponge toxin kills lung and breast cancer cells in mice

Peloruside A is a potent toxin that was isolated from a New Zealand marine sponge. It has a similar mechanism of action to the commonly used taxane-type anticancer drugs, including paclitaxel and docetaxel, that block the action

Protein associated with breast cancer metastasis

Breast cancer is one of the leading causes of death in women. Although there have been significant advances in diagnosis and treatment, therapy of breast cancer which has spread to other organs remains a significant challenge. It

Sugars in circulating blood reflect breast cancer biology

In our studies, consisting of measurements and analyses, we have shown that the sugar composition in the serum of breast cancer patients reflects the biology of their breast tumours. Patients with different kinds of breast tumours have

A method for studying mouse mammary tumorigenesis

Metastasis is the last step of primary breast cancer progression in which cells from the primary tumor leave and go to other organs. Breast cancer cells often metastasize to the lung, among other organs. Each step in

The art to irradiate the Internal Mammary Nodes (IMN) in breast cancer patients

Radiation therapy (RT) has demonstrated strong clinical benefit in patients with breast conservative surgery or with radical mastectomy and who are at high risk for relapse. Unfortunately, this benefit was counterbalanced by an increased risk for death

Breast cancer cells change and adapt during disease progression

A diagnosis of breast cancer usually includes characterisation of the breast cancer cells: determining if the tumour cells have hormone receptors and other proteins which will help to decide the best treatment options for the patient. This

Doctors, look up! Lack of eye contact reduces trust

Trust between breast cancer patients and their oncologist is crucial for good quality breast cancer care. It is associated with beneficial outcomes, such as a decrease in patients’ fear and better adherence. Patients’ trust was earlier shown