Tag Archives: c-ring

Clues for innovative therapies targeting the c-ring of the F1FO-ATP synthase

Increasing evidence points out that the ATP synthase/hydrolase, also known as F1FO-complex, can be the key enzymatic switch between cell life and death. So, the enzyme complex, which bears the task of building most cellular ATP, the

Multiple tasks for the c-ring of the F1FO-ATP synthase

The F1FO-ATP synthase is the only enzyme in nature endowed with bi-functional catalytic mechanism of synthesis and hydrolysis of ATP. The enzyme complex is hosted in the inner mitochondrial membrane in eukaryotes and in the plasma-membrane in