Tag Archives: designer drugs

Estimating effects of new psychoactive substances (NPS) based on in vitro neurotoxicity data

The use of new psychoactive substances (NPS) is increasing and currently > 600 NPS have been reported. However, limited information on neuropharmacological and toxicological effects of NPS is available, hampering risk characterization. We reviewed the literature on

New psychoactive substances and drugs of abuse inhibit the reuptake of monoamines via monoamine transporters

The use of illicit drugs is high and 5% of the population worldwide used an illicit drug in the last year. While the prevalence of use of these common drugs is decreasing, the use of new psychoactive

New psychoactive substances and drugs of abuse inhibit neuronal activity

New psychoactive substances (NPS), also known as ‘legal highs’, ‘bath salts’ or ‘research chemicals’, appeared on the drug market around a decade ago. Even though they account for only a small proportion of the market, NPS encompass