Tag Archives: DMSO
Organic synthesis provides 17,18-EpETE and isoleukotoxin diol in optically active forms
The epoxide ring opening of the trimethylsilyl substituted epoxy alcohol 1 (R1 = H) by CH3S(O)CH2Na (NaDMSO) produces anion 2 as the transient species, which undergoes an unusual reaction rather than the Peterson olefination (Fig. 1). When
Another aspect in use of DMSO in medicinal chemistry
Drug discovery and development might be a long and arduous journey. A brave traveler steps forward enthusiastically, but unfortunately and almost always gets lost and comes back to the beginning, and thus only rarely gains a fruit
