Tag Archives: drugs
Identifying doses in commercial liquid drugs sterilized by ionizing radiation
Drug sterilization with ionizing radiation, such as gamma-radiation using doses up to 25 kGy is a well-established technology, which can adequately eliminate bacteria by breaking down their DNA. This method is gaining ground due to its numerous
How cancer cells resist the action of microtubule-targeting chemotherapeutic drugs? A study of β-tubulin mutations
Microtubules (MTs) are essential structural components of cells. They are made up of polymers of protein subunits of α,β-tubulin and are highly dynamic, undergoing rapid phases of assembly and disassembly. The dynamic behavior of MTs is essential
Using Darwin to discover new advanced materials
The process of evolution, first described in detail by Charles Darwin, has resulted in the amazing diversity of plants and animals in our world, each subgroup shaped by the effects of the different environments in which they
Pharmacist’s role to help patients get the most out of their medications
Many patients do not adhere well to their prescribed medication regimens. Evidence shows that improving medication adherence leads to lower overall health care use and costs. As a result, healthcare stakeholders are increasingly interested in improving patient
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
Obesity causes lung dysfunction and breathing troubles by increased cysteinyl leukotrienes pathway
Increased body weight is a chronic health problem which has emanated from the globalized food market and dietary habit. This has led to the different types of ailments which occur in obese individual simultaneously and referred to
A potentially lethal condition that may occur in psychiatric patients
Antipsychotic drugs are commonly prescribed in patients with various psychiatric illnesses (e.g. psychosis, schizophrenia, aggressive behavior, etc.). A neurological emergency may arise characterized by muscle rigidity and damage, increased body temperature and cardio-respiratory system instability in patients
Mass spec: a powerful weapon in the battle against illegal polypeptide drugs
The occurrence of illegal medicines is a well-established global problem and concerns mostly small molecules (Molecular weight below 900 Da), including sildenafil (active pharmaceutical ingredient of Viagra® and Cialis®) and analogues, anti-biotics, HIV medication, anti-malaria products, anabolic
Understanding the evolution of protein dynamics can lead to more effective non-toxic drug therapies
Proteins are macromolecules that play important roles in all living organisms. They protect the body from viruses and bacteria, control chemical reactions, transmit signals between cells and organs, and transport other molecules to places in the body
Changing the image of Gout
Gout is the most common arthritis of patients over 40 years of age. Many phycians treat these gouty attacks but do not realize that they should also care for the underlying urate accumulation. It is not only
