Tag Archives: glioma

The voltage-gated potassium channel, Kv1.3, at the crossroads of glial functions in glioma

The voltage-gated potassium channel, Kv1.3, at the crossroads of glial functions in glioma

Glioblastoma multiforme (GBM) is one of the most lethal cancers in adult humans, with a frequency of 6:100.000 people. Despite the current three-modality therapy, which includes surgery, radiation and chemotherapy, the clinical outcome of GBM patients remains

When inhibition means activation: towards the disclosure of the role of PKCδ in cell demise

Gliomas are highly invasive tumor cells which synthesize numbers of proteins/enzymes performing different functions. Some of these enzymes affect the cells survival, proliferation and migration, the others force the cells to commit suicide known under the term

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

In people diagnosed with malignant brain tumors, the prescribed treatment is often radiation and chemotherapy; however, these treatments severely affect the immune system, increasing the chance of early death. Radiation in particular has been known to cause