Tag Archives: heme

Getting metals into mitochondria

Metallurgy and the mitochondrion.

Scientists consider mitochondria, an organelle within cells, as a power plant. But mitochondria are also a site for metallurgy. There iron enters heme, the compound that binds oxygen in hemoglobin and certain other proteins, or helps form

Heme: an old player with a novel mechanism in cardiac muscle contractility

Heme is a complex containing iron and protoporphyrin IX and it is commonly bound to proteins involved in oxygen transport, detoxification and energy production. However, this molecule has been known to have toxic effects in the heart.