Tag Archives: Huntington

Disengaging ATF6 from DREAM for neuroprotection

Disengaging ATF6 from dream for neuroprotection

To study early changes in neuronal function during the pre-symptomatic phase of a given neurodegenerative disease is very important. It could deliver early diagnostic markers, offer prognostic clues about disease progression and uncover novel therapeutic targets for

DNAJB6 – an early-stage scavenger of amyloidogenic peptides

A molecular chaperone has been discovered that binds to amyloidogenic peptides and delays onset of aggregation and neurodegeneration. Chaperone proteins, existing in the cells of all organisms, are helper proteins that serve to keep the proteins in