Tag Archives: membrane

Computational refinement and validation protocol for proteins

HIV protects itself using a membrane layer of lipids which covers all proteins which could potentially be targeted by drugs. The only exposed proteins, gp120 and gp41 form spikes that protrude out of the lipid membrane.  These

Janus subcompartmentalized microreactors

When we are sick and have to take medicine, the first thing we do, is reading the package leaflet. We want to know the potential side effects of the drug. Sometimes the side effect of one drug

Oxygen-transfer performance of a new, very low-volume membrane oxygenator

During heart surgery, an external system (extracorporeal circulation) is often needed to replace the normal function of the heart and lungs to ensure blood circulation to the brain and all other organs. One key element of this

Granule formation in pancreatic acinar cells

The pancreas is an important gland organ within the digestive and endocrine system of vertebrates. It is both an endocrine and exocrine gland. The endocrine part produces several important hormones such as insulin which are released in

Tailored-pore materials on polymeric membranes for gas separation

Separation operations in the chemical processes are the most energy and money consuming for the large industries and, therefore, one of the most important challenges for the chemical engineers to overcome now and in the next decades

Pass the salt, please! Understanding how cells deal with high salt

Table salt, a molecule made up of the charged ions sodium and chloride, is an essential nutrient fundamental to life and once worth its weight in gold. Historically a precious commodity, salt also helped civilizations develop because

A wearable UV-LED medical device for automatic disinfection of stethoscope membrane

The medical literature has demonstrated the importance of healthcare-associated infections ( HAI ), which are an huge worldwide problem because of health complications, mortality ( EU + USA 140.000 death/year ), length of hospitalization and costs for

Participation of secreted protein L5 in formation of outer membrane vesicles produced by Lysobacter sp. XL1

Formation of outer membrane vesicles is a physiological feature of Gram-negative bacteria. Vesicles formation is result of splitting off the evagination of bacterial outer membrane. Its size varies from 20 to 300 nm. During formation of vesicles,

One for two – one medicine against two diseases

Superficial fungal skin infections belong to the most common infections worldwide. They affect more than 20 – 25 % of the world’s population with an increasing trend due to an increasing life expectancy and decreasing immunity of

A Tat ménage a trois – when it comes to Tat secretion two Tat’s are essential, but the third one makes it that much better

The membrane is the cellular barrier that keeps the inside of a cell separate from the outside, but in order to survive molecules and proteins do need to cross this barrier. Water and small molecules can do

An intracellular membrane system helps cells to divide

Cell duplication is the fundamental requirement for the development of multi-cellular organisms, a process that relies on two basic events: replication of the genetic information and the consequent separation of this information into two daughter cells. The