Tag Archives: naltrexone

Clinically utilized nalfurafine combined with naltrexone prevents excessive alcohol drinking and “relapse”

AoS. Clinically utilized nalfurafine combined with naltrexone prevents excessive alcohol drinking

Alcohol addiction poses massive public health costs [~15 million adult alcoholics with economic cost > $200 billion/year in the US]. Pharmacological studies in rodents have demonstrated that kappa-opioid receptor (KOR) agonists decrease alcohol drinking and reward. However,