Tag Archives: NF-кB

Skewed signaling through RAGE strength the tumor growth-promoting activities of M2 macrophages

Skewed signaling through RAGE strength. AoS

Tumors are complex tissues composed by both non-cellular components, mainly matrix proteins, and different stromal cell types, which are under an active cross talk with tumor cells. Tumor-associated macrophages (TAMs) are the major leukocyte population among the